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IL12RB1 Protein (AA 24-540) (Fc Tag)

IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504432
发货至: 中国
  • 抗原 See all IL12RB1 蛋白
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    蛋白类型
    Recombinant
    产品特性
    AA 24-540
    宿主
    • 13
    • 5
    • 1
    资源
    • 9
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This IL12RB1 protein is labelled with Fc Tag.
    原理
    Human IL-12 R beta 1/CD212 Protein
    序列
    Cys24-Glu540
    产品特性
    Recombinant Human IL-12 R beta 1/CD212 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Cys24-Glu540.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product IL12RB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    别名
    IL-12 R beta 1 (IL12RB1 产品)
    别名
    Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
    背景
    Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. Lung and T cell IL12RB1 expression is allele-biased, and the extent to which cells express one IL12RB1 allele is unaffected by activation. Furthermore following its expression the IL12RB1 pre-mRNA is processed into either IL12RB1 Isoform 1 (IL12Rβ1, a positive regulator of IL12 responsiveness) or IL12RB1 Isoform 2 (a protein of heretofore unknown function).
    分子量
    83.85 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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