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IL12RB1 Protein (AA 24-540) (Fc Tag)

IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
产品编号 ABIN6809859
发货至: 中国
  • 抗原 See all IL12RB1 蛋白
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-540
    宿主
    • 13
    • 5
    • 1
    资源
    • 9
    • 4
    • 3
    • 2
    HEK-293 Cells
    标记
    This IL12RB1 protein is labelled with Fc Tag.
    序列
    AA 24-540
    纯度
    >95 % as determined by reduced SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL12RB1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    别名
    IL-12 R beta 1 (IL12RB1 产品)
    别名
    Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
    背景
    The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
    分子量
    83.5 kDa
    NCBI登录号
    NP_005526
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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