FASL Protein (AA 139-281, Soluble) (Fc Tag)
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- 抗原 See all FASL 蛋白
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Soluble, AA 139-281
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宿主
- 人, 小鼠
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资源
- HEK-293 Cells
- 标记
- This FASL protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to human and mouse Fas.
- 交叉反应
- 人, 小鼠
- 产品特性
- Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FASL 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- 别名
- FasL (FASL 产品)
- 别名
- ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
- 背景
- Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
- 分子量
- ~50kDa (SDS-PAGE)
- UniProt
- P48023
- 途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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