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FASL Protein (Fc Tag)

FASL 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6964357
发货至: 中国
  • 抗原 See all FASL 蛋白
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    蛋白类型
    Recombinant
    宿主
    • 17
    • 11
    • 4
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    • 2
    • 2
    • 1
    • 1
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    • 1
    资源
    • 11
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    HEK-293 Cells
    标记
    This FASL protein is labelled with Fc Tag.
    原理
    Recombinant human FASLG with N-terminal human Fc tag
    特异性
    HFc (Glu99-Ala330) FASLG (Pro134-Leu281)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product FASL 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    别名
    FASLG (FASL 产品)
    别名
    ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
    背景
    Synonymes: ALPS1B, APT1LG1, APTL, CD95-L, CD95L, CD178, FASL, TNFSF6, TNLG1A
    Description: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
    分子量
    predicted molecular mass of 43.0 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FASLG is 35-55kDa due to glycosylation.
    UniProt
    P48023
    途径
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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