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FASL Protein (AA 18-111) (DYKDDDDK Tag)

FASL 宿主: 人, 小鼠 宿主: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
产品编号 ABIN5564380
发货至: 中国
  • 抗原 See all FASL 蛋白
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 18-111
    宿主
    • 18
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    资源
    • 11
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This FASL protein is labelled with DYKDDDDK Tag.
    应用范围
    SDS-PAGE (SDS)
    特异性
    Binds to human and mouse Fas.
    交叉反应
    人, 小鼠
    产品特性
    Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
    纯度
    >95 % (SDS-PAGE)
    内毒素水平
    <0.02EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product FASL 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.

    限制
    仅限研究用
  • 状态
    Solid
    浓度
    Lot specific
    缓冲液
    Lyophilized. Contains PBS.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    别名
    FasL (FASL 产品)
    别名
    ALPS1B Protein, APT1LG1 Protein, APTL Protein, CD178 Protein, CD95-L Protein, CD95L Protein, FASL Protein, TNFSF6 Protein, fasl Protein, Fas-L Protein, Faslg Protein, Tnfsf6 Protein, gld Protein, Apt1Lg1 Protein, Fasl Protein, FASLG Protein, zgc:162027 Protein, Fas ligand Protein, Fas ligand L homeolog Protein, Fas ligand (TNF superfamily, member 6) Protein, FASLG Protein, faslg.L Protein, Fasl Protein, Faslg Protein, faslg Protein
    背景
    MultimericFasL™ is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively mimics the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
    分子量
    ~40kDa (SDS-PAGE)
    UniProt
    P48023
    途径
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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