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TRAF3 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

TRAF3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2734113
发货至: 中国
  • 抗原 See all TRAF3 蛋白
    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 3
    宿主
    • 5
    • 1
    资源
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This TRAF3 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human TRAF3 / CRAF1 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TRAF3 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
    别名
    Traf3,craf1 (TRAF3 产品)
    别名
    CAP-1 Protein, CAP1 Protein, CD40bp Protein, CRAF1 Protein, IIAE5 Protein, LAP1 Protein, AI528849 Protein, T-BAM Protein, amn Protein, TNF receptor associated factor 3 Protein, TNF receptor-associated factor 3 Protein, Tnf receptor-associated factor 3 Protein, TRAF3 Protein, Traf3 Protein
    背景
    The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
    分子量
    64.3 kDa
    NCBI登录号
    NP_003291
    途径
    NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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