TRAF3 产品
(TNF Receptor-Associated Factor 3 (TRAF3))
Categories
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010].
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Featured TRAF3 Categories
TRAF3 抗体
High quality antibodies with extensive validation data.
TRAF3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TRAF3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TRAF3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (5)
Cat. No.
ABIN738921
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7192878
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7172236
Quantity
100 μg
Datasheet
Datasheet
Recommended TRAF3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960018
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5690963
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385595
Quantity
96 tests
Datasheet
Datasheet
Recommended TRAF3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125408
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323497
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323499
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our TRAF3 Products
: "Chandipura virus changes cellular miRNome in human microglial cells." in: Journal of medical virology, (2019) (PubMed).: "The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development." in: Science signaling, Vol. 8, Issue 392, pp. ra88, (2015) (PubMed).
: "The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2." in: Nature immunology, Vol. 15, Issue 9, pp. 866-74, (2014) (PubMed).
: "ACRP30, a new hormone controlling fat and glucose metabolism." in: European journal of pharmacology, Vol. 440, Issue 2-3, pp. 213-21, (2002) (PubMed).
: "TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 9, pp. 5084-96, (2000) (PubMed).
: "TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF-kappaB activation." in: Molecular immunology, Vol. 36, Issue 10, pp. 647-58, (1999) (PubMed).
: "Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses." in: Immunity, Vol. 5, Issue 5, pp. 407-15, (1997) (PubMed).
: "Involvement of CRAF1, a relative of TRAF, in CD40 signaling." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1494-8, (1995) (PubMed).
Synonyms and alternative names related to TRAF3
TNF receptor associated factor 3 (TRAF3), TNF receptor-associated factor 3 (Traf3), Tnf receptor-associated factor 3 (Traf3), AI528849, amn, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, T-BAMProtein level used designations for TRAF3
- CD40 associated protein 1
- CD40 binding protein
- CD40 receptor associated factor 1
- LMP1-associated protein 1
- CD40 receptor-associated factor 1
- TRAFAMN
- TNF receptor-associated factor 3
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