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TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) 产品

(TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity).

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Featured TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Categories

TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) 抗体

High quality antibodies with extensive validation data.

TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) 抗体

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Cat. No. ABIN6261299
Quantity 100 μL
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Reactivity Human, Mouse, Rat
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Cat. No. ABIN5711936
Quantity 0.1 mg
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Cat. No. ABIN7171526
Quantity 100 μg
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Recommended TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) ELISA试剂盒

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Cat. No.
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Reactivity Human
Analytical Method
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Cat. No. ABIN1160841
Quantity 96 tests
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Reactivity Mouse
Analytical Method
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Cat. No. ABIN1160842
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
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Cat. No. ABIN1160840
Quantity 96 tests
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Recommended TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) 蛋白

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Cat. No. ABIN1323477
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Cat. No. ABIN3096018
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Latest Publications for our TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Products

Hsu, Wang, Lin, Huang, Lai, Liao, Chen: "Adducin-1 is essential for spindle pole integrity through its interaction with TPX2." in: EMBO reports, Vol. 19, Issue 8, (2019) (PubMed).

van Gijn, Wierenga, van den Tempel, Kok, Heijink, Spierings, Foijer, van Vugt, Fehrmann: "TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells." in: Oncogene, Vol. 38, Issue 6, pp. 852-867, (2019) (PubMed).

Manukyan, Sargsyan, Parsons, Stukenberg: "P190RhoGAP prevents mitotic spindle fragmentation and is required to activate Aurora A kinase at acentriolar poles." in: Chromosoma, Vol. 127, Issue 3, pp. 375-386, (2019) (PubMed).

Connell, Chen, Jiang, Kuan, Fotovati, Chu, He, Lengyell, Li, Kroll, Li, Goldowitz, Frappart, Ploubidou, Patel, Pilarski, Simpson, Lange, Allan, Maxwell: "HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development." in: eLife, Vol. 6, (2018) (PubMed).

Park, Kwon, Kim, Lee, Song: "USP35 regulates mitotic progression by modulating the stability of Aurora B." in: Nature communications, Vol. 9, Issue 1, pp. 688, (2018) (PubMed).

Mann, Wadsworth: "Distribution of Eg5 and TPX2 in mitosis: Insight from CRISPR tagged cells." in: Cytoskeleton (Hoboken, N.J.), Vol. 75, Issue 12, pp. 508-521, (2018) (PubMed).

Franciosi, Manandhar, Conti: "FSH Regulates mRNA Translation in Mouse Oocytes and Promotes Developmental Competence." in: Endocrinology, Vol. 157, Issue 2, pp. 872-82, (2016) (PubMed).

Rao, Flores-Rodriguez, Page, Wong, Robinson, Chircop: "The Clathrin-dependent Spindle Proteome." in: Molecular & cellular proteomics : MCP, Vol. 15, Issue 8, pp. 2537-53, (2016) (PubMed).

Mann, Balchand, Wadsworth: "Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics." in: Molecular biology of the cell, Vol. 28, Issue 1, pp. 65-75, (2016) (PubMed).

Shim, Perez de Castro, Neumayer, Wang, Park, Sanada, Nguyen: "Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9122-34, (2015) (PubMed).

Synonyms and alternative names related to TPX2, Microtubule-Associated, Homolog (Xenopus Laevis)

TPX2, microtubule nucleation factor (TPX2), TPX2, microtubule-associated (Tpx2), TPX2, microtubule nucleation factor (Tpx2), TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), TPX2, microtubule-associated S homeolog (tpx2.S), TPX2, microtubule-associated L homeolog (tpx2.L), 2610005B21Rik, C20orf1, C20orf2, DIL-2, dil-2, DIL2, dil2, FLS353, GD:C20orf1, HCA519, HCTP4, hctp4, p100, REPP86, repp86, TPX2, tpx2

Protein level used designations for TPX2, Microtubule-Associated, Homolog (Xenopus Laevis)

  • TPX2, microtubule-associated protein homolog
  • TPX2, microtubule-associated, homolog
  • differentially expressed in cancerous and non-cancerous lung cells 2
  • differentially expressed in lung cells
  • hepatocellular carcinoma-associated antigen 519
  • preferentially expressed in colorectal cancer
  • protein fls353
  • restricted expression proliferation associated protein 100
  • restricted expression proliferation-associated protein 100
  • targeting protein for Xklp2
  • TPX2, microtubule-associated, homolog (Xenopus laevis)
  • targeting protein for Xklp2-like
  • TPX2 protein, microtubule-associated
  • targeting protein for Xklp2-B
  • targeting protein for Xklp2-A
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