TRAFs and NIK-Associated Protein 抗体
(TRAFs and NIK-Associated Protein (TNAP))
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
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Featured TRAFs and NIK-Associated Protein Categories
TRAFs and NIK-Associated Protein 抗体
High quality antibodies with extensive validation data.
Recommended TRAFs and NIK-Associated Protein 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN3181417
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Goat, Human, Monkey, Pig, Sheep
Application
FACS
Validations
- (2)
Cat. No.
ABIN7013887
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Dog, Goat, Human, Monkey, Pig, Sheep
Application
FACS
Validations
- (2)
Cat. No.
ABIN7013888
Quantity
0.1 mg
Datasheet
Datasheet
Synonyms and alternative names related to TRAFs and NIK-Associated Protein
alkaline phosphatase, liver/bone/kidney (ALPL), alkaline phosphatase, liver/bone/kidney (Alpl), Akp-2, Akp2, AP-TNAP, APTNAP, HOPS, TNAP, TNSALPProtein level used designations for TRAFs and NIK-Associated Protein
- alkaline phosphatase liver/bone/kidney isozyme
- alkaline phosphatase, tissue-nonspecific isozyme
- alkaline phosphomonoesterase
- glycerophosphatase
- liver/bone/kidney-type alkaline phosphatase
- tissue-nonspecific ALP
- alkaline phosphatase 2, liver
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- TRAF3IP2
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- TRAF2
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- Trace Amine Associated Receptor 8
- TRAC
- TRABD2B
- TRABD2A
- TRABD
- TraB
- TRA2B
- TRAIL
- TRAIP
- TRAJ17
- TraK
- TRAK1
- TRAK2
- TRAM1
- TRAM1L1
- TRAM2
- Tramadol
- Trans-Sialidase
- Transcription Factor 24
- Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box)
- Transcription Factor MafK
- Transcription Termination Factor rho
- Transcriptional Adaptor 3
- Transferrin
- Transferrin Receptor
- Transferrin Receptor 2
- Transforming Growth Factor, beta 2
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