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HRAS Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

HRAS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2723051
发货至: 中国
  • 抗原 See all HRAS 蛋白
    HRAS (HRas proto-oncogene, GTPase (HRAS))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 3
    宿主
    • 13
    • 2
    • 2
    • 1
    • 1
    资源
    • 8
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    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This HRAS protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human HRAS (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HRAS 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    HRAS (HRas proto-oncogene, GTPase (HRAS))
    别名
    Hras (HRAS 产品)
    别名
    C-BAS/HAS Protein, C-H-RAS Protein, C-HA-RAS1 Protein, CTLO Protein, H-RASIDX Protein, HAMSV Protein, HRAS1 Protein, K-RAS Protein, N-RAS Protein, RASH1 Protein, hras Protein, zgc:110250 Protein, HRAS Protein, H-RAS Protein, c-H-ras Protein, H-Ras Protein, K-Ras Protein, hras1 Protein, rash1 Protein, ras Protein, N-Ras Protein, c-bas/has Protein, H-ras Protein, Ha-ras Protein, Harvey-ras Protein, Hras-1 Protein, Kras2 Protein, c-Ha-ras Protein, c-rasHa Protein, hrasl Protein, zgc:110734 Protein, HRas proto-oncogene, GTPase Protein, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a Protein, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene Protein, Harvey rat sarcoma viral oncogene homolog L homeolog Protein, Harvey rat sarcoma viral oncogene homolog Protein, Harvey rat sarcoma virus oncogene Protein, NRAS proto-oncogene, GTPase Protein, -Ha-ras Harvey rat sarcoma viral oncogene homolog b Protein, HRAS Protein, hrasa Protein, LOC733587 Protein, Hras Protein, hras.L Protein, hras Protein, NRAS Protein, hrasb Protein
    背景
    This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
    分子量
    21.1 kDa
    NCBI登录号
    NP_001123914
    途径
    p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
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