IL12RB1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all IL12RB1 蛋白
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL12RB1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CD212 / IL12RB1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IL12RB1 蛋白
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Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) protein (His tag)
IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag,AVI tag,Biotin)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) protein (GST tag)IL12RB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (His tag)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 12 Receptor beta 1 (IL12RB1) (AA 24-540) (Active) protein (Fc Tag)IL12RB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 别名
- Cd212,il12rb1 (IL12RB1 产品)
- 别名
- Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein
- 背景
- The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
- 分子量
- 70.4 kDa
- NCBI登录号
- NP_005526
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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