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IL12 蛋白

IL12 宿主: 人 宿主: Insect Cells Recombinant ELISA, BCA
产品编号 ABIN2666983
发货至: 中国
  • 抗原 See all IL12 蛋白
    IL12 (Interleukin 12 (IL12))
    蛋白类型
    Recombinant
    宿主
    • 18
    • 9
    • 4
    • 1
    资源
    • 14
    • 4
    • 4
    • 4
    • 2
    • 1
    Insect Cells
    应用范围
    ELISA, Biochemical Assay (BCA)
    Top Product
    Discover our top product IL12 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.,Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Prior to use, reconstitute the lyophilized powder with 0.2 mLof PBS containing a carrier protein (e.g., 1 % BSA, protease free), pH 7.4. Re-cap vial, vortex. Allow the reconstituted standard to sit at room temperature for 15 minutes, vortex again to mix completely. The reconstituted standard stock solution can be aliquoted into polypropylene vials and stored at -70 °C for up to one month.
    缓冲液
    Lyophilized in sterile-filtered PBS, pH 7.2, containing 1 % BSA.
    注意事项
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    储存条件
    4 °C
    储存方法
    Upon receipt, store unopened vials between 2°C and 8°C immediately and use within 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    IL12 (Interleukin 12 (IL12))
    别名
    IL-12 (IL12 产品)
    别名
    CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, LOC100217488 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p40 Protein, IL12B Protein, IL-12 p35 Protein, interleukin 12B Protein, interleukin 12A Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12B Protein, IL12A Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
    背景
    Bioactive IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 cell development. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells, and macrophages as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD and 40 kD subunits. The disulfide-linked p40 homodimer can bind to IL-12 receptors and antagonize the activities of bioactive IL-12. Recombinant human IL-12 is a 70 kD protein containing a 306 amino acid p40 subunit and a 197 amino acid p35 subunit.
    途径
    JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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