TGFB1 Protein (AA 279-390)
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- 抗原 See all TGFB1 蛋白
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 279-390
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宿主
- 人
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资源
- CHO Cells
- 应用范围
- ELISA, Intracellular Flow Cytometry (ICFC), Flow Cytometry (FACS)
- 纯度
- > 98 % , as determined by Coomassie stained SDS-PAGE prior to lyophilization.
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- Discover our top product TGFB1 蛋白
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Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) protein (His-Avi Tag,Biotin)
TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, beta 1 (TGFB1) proteinTGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 1 (TGFB1) (AA 200-503) (Active) protein (GST tag)TGFB1 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) protein (AVI tag,Biotin)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-390) (Active) protein (His tag)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-390) (Active) protein (His tag,AVI tag,Biotin)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) (Active) protein (His tag,AVI tag,Biotin)TGFB1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Transforming Growth Factor, beta 1 (TGFB1) (AA 281-390) protein (GST tag)TGFB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) protein (GST tag)TGFB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) protein (His tag)TGFB1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 应用备注
- Optimal working dilution should be determined by the investigator.,Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Prior to use, reconstitute the lyophilized powder with 0.2 mLof PBS containing a carrier protein (e.g., 1 % BSA, protease free), pH 7.4. Re-cap vial, vortex. Allow the reconstituted standard to sit at room temperature for 15 minutes, vortex again to mix completely. The reconstituted standard stock solution can be aliquoted into polypropylene vials and stored at -70 °C for up to one month.
- 缓冲液
- Lyophilized in sterile-filtered PBS, pH 7.2, containing 1 % BSA.
- 注意事项
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt, store unopened vials between 2°C and 8°C immediately and use within 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- 别名
- TGF-Beta1 (TGFB1 产品)
- 别名
- CED Protein, DPD1 Protein, LAP Protein, TGFB Protein, TGFbeta Protein, TGF-beta Protein, TGF-BETA-1 Protein, TGF-beta5 Protein, ced Protein, dpd1 Protein, lap Protein, tgf-beta Protein, tgfb Protein, tgfb5 Protein, tgfbeta Protein, TGF-beta1 Protein, TGFbeta1 Protein, Tgfb Protein, Tgfb-1 Protein, ai39657 Protein, tgfb1 Protein, wu:fb13a07 Protein, xx:ai39657 Protein, TGFB1 Protein, csd Protein, cdb1 Protein, cdg2 Protein, csd1 Protein, csd2 Protein, csd3 Protein, ebmd Protein, lcd1 Protein, bigh3 Protein, cdgg1 Protein, betaig-h3 Protein, TGFB4 Protein, transforming growth factor beta 1 Protein, transforming growth factor beta-1 Protein, transforming growth factor beta 1 L homeolog Protein, transforming growth factor, beta 1 Protein, transforming growth factor, beta 1a Protein, transforming growth factor beta induced L homeolog Protein, TGFB1 Protein, Tgfb1 Protein, tgfb1.L Protein, tgfb1a Protein, tgfbi.L Protein
- 背景
- Transforming growth factor beta 1 (TGF-β1) is a member of the transforming growth factor beta superfamily of cytokines. The TGF-β1 precursor contains 390 amino acids with an N-terminal signal peptide of 29 amino acids required for secretion from a cell, a 249 amino acid pro-region (latency associated peptide or LAP), and a 112 amino acid C-terminal region that becomes the active TGF-β1 upon activation. Both LAP and TGF-β1 exist as homodimers in circulation, but the disulfide linked homodimers of LAP and TGF-β1 remain non-covalently associated, forming the small latent TGF-β complex (SLC, 100 kD). The large latent TGF-β complex (LLC, 235-260 kD) contains a third component, the latent TGF-β binding protein (LTBP), which is linked to LAP by a single disulfide bond. LTBP does not confer latency but is for efficient secretion of the complex to extracellular sites. Free active TGF-β1 can be released (activated) by many factors, including enzymes and low or high pH . TGF-β1 is nearly 100 % conserved across mammalian species. It has diverse biological functions in multiple cellular processes such as regulating proliferation and differentiation of various cell types. TGF-β1 is also an important immunoregulatory cytokine, which is involved in the maintenance of self-tolerance, Th17 differentiation, and T-cell homeostasis.
- 分子量
- Recombinant human TGF-β1 exists as a disulfide linked homodimer, consisting of two 112 amino acid monomers, each with a predicted molecular mass of approximately 12.8 kDa. The non-reduced protein migrates as a homodimer, at approximately 26 kDa by SDS-PAG
- 途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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