TIM3 Protein (AA 22-200) (Fc Tag,His tag)
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- 抗原 See all TIM3 (TIM 3) 蛋白
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-200
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宿主
- 人
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资源
- 人细胞
- 标记
- This TIM3 protein is labelled with Fc Tag,His tag.
- 原理
- Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
- 序列
- SEVEYRAEVG QNAYLPCFYT PAAPGNLVPV CWGKGACPVF ECGNVVLRTD ERDVNYWTSR YWLNGDFRKG DVSLTIENVT LADSGIYCCR IQIPGIMNDE KFNLKLVIKP AKVTPAPTLQ RDFTAAFPRM LTTRGHGPAE TQTLGSLPDI NLTQISTLAN ELRDSRLAND LRDSGATIRV DDIEGRMDEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSREE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH
- 产品特性
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Recombinant Human T Cell Immunoglobulin and Mucin Domain-3/TIM-3/HAVCR2 (C-Fc-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TIM 3 蛋白
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Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) protein (His tag)
TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) protein (His-Avi Tag,Biotin)TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-191) protein (His tag)TIM 3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (mFc-His Tag)TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-200) (Active) protein (His tag,AVI tag,Biotin)TIM 3 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (His tag)TIM 3 宿主: Marmoset 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 20-191) protein (His tag)TIM 3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (Active) protein (Fc Tag)TIM 3 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 20-193) protein (His tag)TIM 3 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Hepatitis A Virus Cellular Receptor 2 (TIM 3) protein (Fc Tag)TIM 3 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- T-Cell Membrane Protein 3/TIM-3 (TIM 3 产品)
- 别名
- HAVCR2 Protein, MGC140131 Protein, HAVcr-2 Protein, KIM-3 Protein, TIM3 Protein, TIMD-3 Protein, TIMD3 Protein, Tim-3 Protein, TIM-3 Protein, Tim3 Protein, Timd3 Protein, tim3 Protein, hepatitis A virus cellular receptor 2 Protein, HAVCR2 Protein, Havcr2 Protein
- 物质类
- Virus
- 背景
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Recombinant Human T-Cell Membrane Protein 3/TIM-3 produced by transfected human cells is a secreted protein with sequence (Ser22-Arg200) of Human TIM3 fused with a FC-6His tag at the C-terminus.
Hepatitis A virus cellular receptor 2 (HAVCR2) is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. - 分子量
- 47.7 kDa
- UniProt
- Q8TDQ0
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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