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IL-6 Protein (AA 25-211, Extracellular Domain) (Fc Tag)

IL6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
产品编号 ABIN1344242
发货至: 中国
  • 抗原 See all IL-6 (IL6) 蛋白
    IL-6 (IL6) (Interleukin 6 (IL6))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    Extracellular Domain, AA 25-211
    宿主
    • 30
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    小鼠
    资源
    • 47
    • 24
    • 19
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This IL-6 protein is labelled with Fc Tag.
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    小鼠
    产品特性
    The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2.
    纯度
    >95 % (SDS-PAGE)
    内毒素水平
    <0.01EU/μg protein (LAL test, Lonza).
    Top Product
    Discover our top product IL6 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Promotes growth of hybridoma/plasma cells at concentration <0.1ng /ml.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with 100 μL sterile water.
    浓度
    Lot specific
    缓冲液
    Lyophilized. Contains PBS.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
    有效期
    12 months
  • 抗原
    IL-6 (IL6) (Interleukin 6 (IL6))
    别名
    IL-6 (IL6 产品)
    别名
    BSF2 Protein, HGF Protein, HSF Protein, IFNB2 Protein, IL-6 Protein, Il-6 Protein, ILg6 Protein, Ifnb2 Protein, il6 Protein, CHIL-6 Protein, interleukin 6 Protein, interleukin-6 Protein, IL6 Protein, Il6 Protein, il-6 Protein, IL-6 Protein
    背景
    Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22 kDa-28 kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
    分子量
    50kDa
    UniProt
    P08505
    途径
    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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