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IL-6 Protein (AA 25-211) (His tag)

IL6 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2018146
发货至: 中国
  • 抗原 See all IL-6 (IL6) 蛋白
    IL-6 (IL6) (Interleukin 6 (IL6))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 25-211
    宿主
    • 33
    • 17
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
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    • 4
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    小鼠
    资源
    • 52
    • 24
    • 21
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    CHO Cells
    标记
    This IL-6 protein is labelled with His tag.
    产品特性
    ED50 < 3 pg /mL, measured in a bioassay using 7TD1 cells.
    AA 25-211, expressed with C-terminal 6xHis.
    纯度
    > 95 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant murine Interleukin-6 (IL-6), His, Murine remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, murine Interleukin-6 (IL-6), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    IL-6 (IL6) (Interleukin 6 (IL6))
    别名
    Interleukin-6 (IL-6) (IL6 产品)
    别名
    BSF2 Protein, HGF Protein, HSF Protein, IFNB2 Protein, IL-6 Protein, Il-6 Protein, ILg6 Protein, Ifnb2 Protein, il6 Protein, CHIL-6 Protein, interleukin 6 Protein, interleukin-6 Protein, IL6 Protein, Il6 Protein, il-6 Protein, IL-6 Protein
    背景
    Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.
    Synonyms: 26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
    分子量
    24-26 kDa, observed by reducing SDS-PAGE.
    UniProt
    P08505
    途径
    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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