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CTLA4 Protein (His tag)

CTLA4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098772
发货至: 中国
  • 抗原 See all CTLA4 蛋白
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    蛋白类型
    Recombinant
    宿主
    • 37
    • 18
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    资源
    • 33
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    • 1
    大肠杆菌(E. Coli)
    标记
    This CTLA4 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product CTLA4 蛋白
  • 说明

    Synonyms: Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, CD, CD152, CELIAC3, GRD4, GSE, ICOS, IDDM12

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CTLA4 (CTLA4 产品)
    别名
    CTLA-4 Protein, CTLA4 Protein, CD152 Protein, Cd152 Protein, Ctla-4 Protein, Ly-56 Protein, CD Protein, CELIAC3 Protein, GRD4 Protein, GSE Protein, IDDM12 Protein, sCTLA4 Protein, cytotoxic T-lymphocyte associated protein 4 Protein, cytotoxic T-lymphocyte-associated protein 4 Protein, CTLA4 Protein, Ctla4 Protein
    背景
    CTLA4 is a member of the immunoglobulin superfamily and transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Recombinant human CTLA4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    15.9 kDa (149aa)
    NCBI登录号
    NP_005205
    途径
    Cancer Immune Checkpoints
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