anti-豚鼠 MAP2K3 抗体 for Western Blotting

Recommended MAP2K3 Antibody (supplied by: Log in to see )

抗原
Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) 抗体
  • Mkk3
  • MAPKK3
  • MEK3
  • MKK3
  • PRKMK3
  • SAPKK-2
  • SAPKK2
  • AW212142
  • Prkmk3
  • mMKK3b
  • map2k3
  • zMKK3
  • MAP kinase activator XMEK3
  • mitogen activated protein kinase kinase 3
  • mitogen-activated protein kinase kinase 3
  • mitogen-activated protein kinase kinase 6
  • map2k3
  • Map2k3
  • MAP2K3
  • map2k6
抗原表位
C-Term
35
28
16
13
12
11
10
10
10
7
7
6
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
330
167
154
55
39
5
4
4
3
2
1
1
1
1
宿主

225
105
克隆类型
多克隆
标记
This MAP2K3 antibody is un-conjugated
8
8
7
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
287
142
115
83
68
26
24
17
10
7
3
1
1
1
选项
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产品编号 ABIN2777129
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.8412476 ABIN2777128 IHC WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN320697 WB Rabbit IgG C-Term Log in to see Polyclonal 0

General

抗原 Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) 抗体
抗原表位 C-Term
(35), (28), (16), (13), (12), (11), (10), (10), (10), (7), (7), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
(330), (167), (154), (55), (39), (5), (4), (4), (3), (2), (1), (1), (1), (1)
宿主
(225), (105)
克隆类型
多克隆
标记 This MAP2K3 antibody is un-conjugated
(8), (8), (7), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(287), (142), (115), (83), (68), (26), (24), (17), (10), (7), (3), (1), (1), (1)
Pubmed 找到1个引用
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MAP2K3抗体详情

MAP2K3目标详情 使用细节 贮存及处理 References for anti-MAP2K3 antibody (ABIN2777129) 图像
Blocking Peptide Blocking peptide for this product available: ABIN979769
序列 EEPSPQLPAD RFSPEFVDFT AQCLRKNPAE RMSYLELMEH PFFTLHKTKK
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%
产品特性 This is a rabbit polyclonal antibody against MAP2K3. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human MAP2K3
Plasmids, Primers & others

MAP2K3目标详情

MAP2K3抗体详情 使用细节 贮存及处理 References for anti-MAP2K3 antibody (ABIN2777129) 图像 回页首
抗原
别名 MAP2K3 (MAP2K3 Antibody 摘要)
背景 MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
Alias Symbols: MAPKK3, MEK3, MKK3, PRKMK3, SAPKK2, SAPKK-2
Protein Interaction Partner: UBC, EGFR, MAPK14, MAP3K5, ARRB1, PKN1, ALDOC, APP, LRRK2, MAPK8IP2, MAPK8IP3, MAPK8IP1, SPAG9, MAP3K2, MAP2K3, PPP2R4, MAP3K4, MAP3K3, TINF2, MYC, RPL13, TAOK2, TAOK1, DCTN1, DYRK1B, PLCB2, SMAD7, MAPK12, MAPK3, ELK1, MAP2K6, NPHS1,
Protein Size: 318
分子量 36 kDa
基因ID 5606
NCBI登录号 NM_002756, NP_002747
途径 MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2

使用细节

MAP2K3抗体详情 MAP2K3目标详情 贮存及处理 References for anti-MAP2K3 antibody (ABIN2777129) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 318 AA

限制 仅限研究用

贮存及处理

MAP2K3抗体详情 MAP2K3目标详情 使用细节 References for anti-MAP2K3 antibody (ABIN2777129) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MAP2K3 antibody (ABIN2777129)

MAP2K3抗体详情 MAP2K3目标详情 使用细节 贮存及处理 图像 回页首
背景

Prickett, Brautigan: "Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4217-27, 2007

图像

MAP2K3抗体详情 MAP2K3目标详情 使用细节 贮存及处理 References for anti-MAP2K3 antibody (ABIN2777129) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (C-Term) antibody (ABIN2777129) WB Suggested Anti-MAP2K3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Po...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (C-Term) antibody (ABIN2777129) MAP2K3 antibody - C-terminal region Formalin Fixed Paraffin Embedded Tissue:...