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MAP2K3 抗体 (AA 1-138)

MAP2K3 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E12D11 unconjugated
产品编号 ABIN5542528
发货至: 中国
  • 抗原 See all MAP2K3 抗体
    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
    抗原表位
    • 25
    • 19
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    • 9
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    AA 1-138
    适用
    • 139
    • 101
    • 81
    • 11
    • 10
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 143
    • 11
    小鼠
    克隆类型
    • 130
    • 24
    单克隆
    标记
    • 70
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
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    • 6
    • 3
    • 3
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    This MAP2K3 antibody is un-conjugated
    应用范围
    • 120
    • 48
    • 40
    • 39
    • 32
    • 28
    • 21
    • 9
    • 8
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human MAP2K3 (AA: 1-138) expressed in E. coli.
    克隆位点
    2E12D11
    亚型
    IgG1
    Top Product
    Discover our top product MAP2K3 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
    别名
    MAP2K3 (MAP2K3 产品)
    别名
    MAPKK3 antibody, MEK3 antibody, MKK3 antibody, PRKMK3 antibody, SAPKK-2 antibody, SAPKK2 antibody, AW212142 antibody, Prkmk3 antibody, mMKK3b antibody, Mkk3 antibody, mitogen-activated protein kinase kinase 3 antibody, mitogen activated protein kinase kinase 3 antibody, MAP kinase activator XMEK3 antibody, MAP2K3 antibody, Map2k3 antibody, map2k3 antibody
    背景

    Description: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.,

    Aliases: MEK3, MKK3, MAPKK3, PRKMK3, SAPKK2, SAPKK-2

    分子量
    39.3 kDa
    基因ID
    5606
    HGNC
    5606
    途径
    MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
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