MAP2K5 抗体
(Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| MAP2K5 抗体 (AA 251-350) | 人 | 兔 Polyclonal |
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| MAP2K5 抗体 (AA 1-448) | 人 | 小鼠 Monoclonal |
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| MAP2K5 抗体 (AA 63-180) | 人 | 小鼠 Monoclonal |
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| MAP2K5 抗体 (AA 1-120) | 人 | 小鼠 Monoclonal |
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|
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| MAP2K5 抗体 (AA 1-190) | 人 | 兔 Polyclonal |
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| Recombinant MAP2K5 抗体 | 人 | 兔 Monoclonal |
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| MAP2K5 抗体 (AA 1-120) | 人 | 小鼠 Monoclonal |
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| MAP2K5 抗体 (AA 127-156) | 人 | 兔 Polyclonal |
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| MAP2K5 抗体 | 人 | 兔 Monoclonal |
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| MAP2K5 抗体 (AA 1-190) | 人 | 兔 Polyclonal |
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| MAP2K5 抗体 (AA 1-190) | 人 | 兔 Polyclonal |
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| MAP2K5 抗体 (AA 9-442) | 人, 大鼠, 猴 | 兔 Polyclonal |
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| MAP2K5 抗体 (pSer137) | 人 | 兔 Polyclonal |
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| MAP2K5 抗体 (AA 142-191) | 人, 大鼠, 小鼠, 猴, 犬, Cow, 马, Pig, 兔, Bat | 兔 Polyclonal |
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| MAP2K5 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| MAP2K5 抗体 (pSer311, pThr315) | 大鼠 | 兔 Polyclonal |
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| MAP2K5 抗体 | 大鼠 | 兔 Polyclonal |
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| MAP2K5 抗体 (AA 1-448) | 人 | 兔 Polyclonal |
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| MAP2K5 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| MAP2K5 抗体 (AA 251-350) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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Primary Antibody
- IHC (Immunohistochemistry (IHC): 已在此应用中经过独立验证)
- WB (Western Blotting: 有验证图片)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
2 references - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 251-350
Independently Validated
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- M1-E6
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-448
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5H11B10
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 63-180
Primary Antibody
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1B4
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-120
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-190
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 24GB295
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1E5
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-120
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB12745
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 127-156
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-190
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-190
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 9-442
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer137
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer311, pThr315
Primary Antibody
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-448
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 385-412, C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 251-350
Latest Publications for our MAP2K5 抗体
: "Melittin inhibits proliferation, migration and invasion of bladder cancer cells by regulating key genes based on bioinformatics and experimental assays." in: Journal of cellular and molecular medicine, Vol. 24, Issue 1, pp. 655-670, (2021) (PubMed).
: "MicroRNA-143 regulates adipogenesis by modulating the MAP2K5-ERK5 signaling." in: Scientific reports, Vol. 4, pp. 3819, (2014) (PubMed).
: "Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells." in: International journal of biological sciences, Vol. 10, Issue 2, pp. 171-80, (2014) (PubMed).
: "Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction." in: Circulation research, Vol. 102, Issue 11, pp. 1416-25, (2008) (PubMed).
: "Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation." in: The Journal of biological chemistry, Vol. 279, Issue 2, pp. 1506-12, (2004) (PubMed).
: "MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation." in: Journal of cell science, Vol. 117, Issue Pt 9, pp. 1773-84, (2004) (PubMed).
: "MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion." in: Oncogene, Vol. 22, Issue 9, pp. 1381-9, (2003) (PubMed).
: "MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival." in: Blood, Vol. 102, Issue 3, pp. 1019-27, (2003) (PubMed).
: "MicroRNA-143 regulates adipogenesis by modulating the MAP2K5-ERK5 signaling." in: Scientific reports, Vol. 4, pp. 3819, (2014) (PubMed).
: "Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells." in: International journal of biological sciences, Vol. 10, Issue 2, pp. 171-80, (2014) (PubMed).
: "Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction." in: Circulation research, Vol. 102, Issue 11, pp. 1416-25, (2008) (PubMed).
: "Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation." in: The Journal of biological chemistry, Vol. 279, Issue 2, pp. 1506-12, (2004) (PubMed).
: "MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation." in: Journal of cell science, Vol. 117, Issue Pt 9, pp. 1773-84, (2004) (PubMed).
: "MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion." in: Oncogene, Vol. 22, Issue 9, pp. 1381-9, (2003) (PubMed).
: "MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival." in: Blood, Vol. 102, Issue 3, pp. 1019-27, (2003) (PubMed).
Aliases for MAP2K5 抗体
mitogen activated protein kinase kinase 5 (Map2k5) 抗体mitogen-activated protein kinase kinase 5 (MAP2K5) 抗体
mitogen-activated protein kinase kinase 5 (Map2k5) 抗体
mitogen-activated protein kinase kinase 5 (map2k5) 抗体
mitogen-activated protein kinase kinase 5 L homeolog (map2k5.L) 抗体
MAP kinase kinase 5 (MKK5) 抗体
AI324775 抗体
AI428457 抗体
ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 抗体
ATMAP2K_ALPHA 抗体
ATMEK5 抗体
ATMKK5 抗体
fb73f02 抗体
HsT17454 抗体
MAP2K_A 抗体
MAP KINASE KINASE 5 抗体
MAP kinase kinase 5 抗体
MAPKK5 抗体
Mapkk5 抗体
Mek5 抗体
MEK5 抗体
PRKMK5 抗体
Prkmk5 抗体
wu:fb73f02 抗体
zgc:172137 抗体
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