IRF3 产品
(Interferon Regulatory Factor 3 (IRF3))
Categories
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
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Featured IRF3 Categories
IRF3 抗体
High quality antibodies with extensive validation data.
IRF3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IRF3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRF3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (5)
Cat. No.
ABIN742688
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7260265
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, ChIP
Validations
- (1)
- (5)
Cat. No.
ABIN6142528
Quantity
100 μL
Datasheet
Datasheet
Recommended IRF3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956910
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN5691022
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967754
Quantity
96 tests
Datasheet
Datasheet
Recommended IRF3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (4)
- (1)
Cat. No.
ABIN1308082
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123496
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308084
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our IRF3 Products
: "RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production." in: PLoS pathogens, Vol. 13, Issue 11, pp. e1006738, (2018) (PubMed).: "AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 195, (2018) (PubMed).
: "Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries." in: Free radical biology & medicine, Vol. 112, pp. 553-566, (2017) (PubMed).
: "Curcumin exerts anti-inflammatory and antioxidative properties in 1-methyl-4-phenylpyridinium ion (MPP(+))-stimulated mesencephalic astrocytes by interference with TLR4 and downstream signaling ..." in: Cell stress & chaperones, Vol. 21, Issue 4, pp. 697-705, (2017) (PubMed).
: "Neddylation controls basal MKK7 kinase activity in breast cancer cells." in: Oncogene, Vol. 35, Issue 20, pp. 2624-33, (2017) (PubMed).
: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).
: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." in: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).
: "NF-κB is involved in the LPS-mediated proliferation and apoptosis of MAC-T epithelial cells as part of the subacute ruminal acidosis response in cows." in: Biotechnology letters, Vol. 38, Issue 11, pp. 1839-1849, (2016) (PubMed).
: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." in: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." in: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).
Synonyms and alternative names related to IRF3
interferon regulatory factor 3 (irf3), interferon regulatory factor 3 (IRF3), interferon regulatory factor 3 (irf-3), interferon regulatory factor 3 (Irf3), interferon regulatory factor 7 (IRF7), C920001K05Rik, IRF-3, irf3, IRF3Protein level used designations for IRF3
- interferon regulatory factor 3
- interferon regulatory factor 3-like
- IRF-3
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