IRF9 产品
(Interferon Regulatory Factor 9 (IRF9))
Categories
Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
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Featured IRF9 Categories
IRF9 抗体
High quality antibodies with extensive validation data.
IRF9 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IRF9 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRF9 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (6)
Cat. No.
ABIN3031426
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
IF, FACS
Validations
- (4)
Cat. No.
ABIN7504160
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN564508
Quantity
100 μg
Datasheet
Datasheet
Recommended IRF9 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956915
Quantity
96 tests
Datasheet
Datasheet
Recommended IRF9 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123501
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308102
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3082016
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our IRF9 Products
: "JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response." in: mBio, Vol. 7, Issue 4, (2016) (PubMed).: "Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway." in: Clinical and experimental immunology, Vol. 178, Issue 3, pp. 548-60, (2014) (PubMed).
: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." in: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).
: "VPg-primed RNA synthesis of norovirus RNA-dependent RNA polymerases by using a novel cell-based assay." in: Journal of virology, Vol. 85, Issue 24, pp. 13027-37, (2011) (PubMed).
: "Structural basis of core promoter recognition in a primitive eukaryote." in: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).
: "Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 24059-65, (1999) (PubMed).
: "Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins." in: European journal of biochemistry / FEBS, Vol. 260, Issue 1, pp. 137-44, (1999) (PubMed).
: "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins." in: Molecular and cellular biology, Vol. 12, Issue 8, pp. 3315-24, (1992) (PubMed).
Synonyms and alternative names related to IRF9
interferon regulatory factor 9 (IRF9), interferon regulatory factor 9 (irf9), interferon regulatory factor 9 (Irf9), IRF-9, Irf-9, ISGF3, ISGF3G, Isgf3g, p48, zgc:92097Protein level used designations for IRF9
- interferon regulatory factor 9
- interferon-stimulated transcription factor 3, gamma 48kDa
- IFN-alpha-responsive transcription factor subunit
- ISGF-3 gamma
- ISGF3 p48 subunit
- interferon-stimulated gene factor 3 gamma
- interferon-stimulated transcription factor 3, gamma (48kD)
- transcriptional regulator ISGF3 subunit gamma
- interferon dependent positive acting transcription factor 3 gamma
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