IRAK4 产品
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Categories
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Featured IRAK4 Categories
IRAK4 抗体
High quality antibodies with extensive validation data.
IRAK4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IRAK4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IRAK4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (6)
Cat. No.
ABIN969218
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (6)
Cat. No.
ABIN7433738
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6142522
Quantity
100 μL
Datasheet
Datasheet
Recommended IRAK4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975850
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957197
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1570807
Quantity
96 tests
Datasheet
Datasheet
Recommended IRAK4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
Cat. No.
ABIN1308067
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570543
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123629
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IRAK4 Products
: "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015) (PubMed).: "An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." in: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).
: "Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4." in: Cancer research, Vol. 72, Issue 23, pp. 6209-16, (2012) (PubMed).
: "IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18276-82, (2010) (PubMed).
: "HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells." in: Scandinavian journal of immunology, Vol. 70, Issue 3, pp. 264-76, (2009) (PubMed).
: "Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6316-27, (2009) (PubMed).
: "IRAK-4--a shared NF-kappaB activator in innate and acquired immunity." in: Trends in immunology, Vol. 27, Issue 12, pp. 566-72, (2006) (PubMed).
: "The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40653-8, (2004) (PubMed).
: "AATF protects neural cells against oxidative damage induced by amyloid beta-peptide." in: Neurobiology of disease, Vol. 16, Issue 1, pp. 150-7, (2004) (PubMed).
: "Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein." in: Journal of leukocyte biology, Vol. 76, Issue 4, pp. 904-8, (2004) (PubMed).
Synonyms and alternative names related to IRAK4
interleukin 1 receptor associated kinase 4 (IRAK4), interleukin 1 receptor associated kinase 4 (irak4), interleukin-1 receptor-associated kinase 4 (irak4), interleukin-1 receptor-associated kinase 4 (Irak4), 8430405M07Rik, 9330209D03Rik, ipd1, IPD1, irak-4, IRAK-4, IRAK4, irak4, ny-ran-64, ny-ren-64, NY-REN-64, ren64, REN64, zgc:55553Protein level used designations for IRAK4
- interleukin-1 receptor-associated kinase 4
- interleukin-1 receptor-associated kinase 4-like
- Interleukin-1 receptor-associated kinase 4
- renal carcinoma antigen NY-REN-64
- NY-REN-64 antigen
- interleukin-1 receptor associated kinase 4
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