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IREM1 产品

(Immune Receptor Expressed On Myeloid Cells 1 (IREM1))
CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6\; MIM 176883) or SHIP (INPP5D\; MIM 601582) (Sui et al., 2004 [PubMed 15184070]\; Alvarez-Errico et al., 2004 [PubMed 15549731]).[supplied by OMIM, Mar 2008].

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Featured IREM1 Categories

IREM1 抗体

High quality antibodies with extensive validation data.

IREM1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IREM1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IREM1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7442012
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN3187967
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN653906
Quantity 400 μL
Datasheet Datasheet

Recommended IREM1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956708
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956707
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1126886
Quantity 96 tests
Datasheet Datasheet

Recommended IREM1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274155
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123404
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3077844
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IREM1 Products

Ueno, Urai, Izawa, Otani, Yanagihara, Kataoka, Takatsuka, Abe, Hasegawa, Shimizu, Kitamura, Kitaura, Miyazaki, Kinjo: "Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils." in: Scientific reports, Vol. 8, Issue 1, pp. 17406, (2018) (PubMed).

Ejarque-Ortiz, Solà, Martínez-Barriocanal, Schwartz, Martín, Peluffo, Sayós: "The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123928, (2015) (PubMed).

Izawa, Isobe, Matsukawa, Ito, Maehara, Takahashi, Yamanishi, Kaitani, Oki, Okumura, Kitamura, Kitaura: "Sphingomyelin and ceramide are physiological ligands for human LMIR3/CD300f, inhibiting FcεRI-mediated mast cell activation." in: The Journal of allergy and clinical immunology, Vol. 133, Issue 1, pp. 270-3.e1-7, (2014) (PubMed).

Asai, Morrison: "The SRC family tyrosine kinase HCK and the ETS family transcription factors SPIB and EHF regulate transcytosis across a human follicle-associated epithelium model." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10395-405, (2013) (PubMed).

Izawa, Kitaura, Yamanishi, Matsuoka, Kaitani, Sugiuchi, Takahashi, Maehara, Enomoto, Oki, Takai, Kitamura: "An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 925-36, (2009) (PubMed).

Synonyms and alternative names related to IREM1

CD300 molecule like family member F (Cd300lf), Cd300 molecule-like family member F (Cd300lf), CD300 molecule like family member f (CD300LF), CD300f, CLIM1, CLM-1, CLM1, Digr2, F730004D16Rik, IgSF13, IREM-1, IREM1, LMIR3, NKIR, Pigr3, RGD1309733

Protein level used designations for IREM1

  • CD300 antigen-like family member F
  • CMRF-35-like molecule 1
  • CMRF35-like molecule 1
  • DC-derived Ig-like receptor 2
  • MAIR-5
  • MAIR-V
  • leukocyte mono-Ig-like receptor 3
  • myeloid-associated immunoglobulin-like receptor 5
  • CD300 antigen like family member F
  • CLM-1
  • CD300 molecule like family member f
  • NK inhibitory receptor
  • immune receptor expressed on myeloid cells 1
  • immunoglobin superfamily member 13
  • immunoglobulin superfamily member 13
  • inhibitory receptor IREM1
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