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IRS2 产品

(Insulin Receptor Substrate 2 (IRS2))
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors.

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured IRS2 Categories

IRS2 抗体

High quality antibodies with extensive validation data.

IRS2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

IRS2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IRS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
  • collections(3)
Cat. No. ABIN5013744
Quantity 100 μL
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (2)
  • collections(2)
Cat. No. ABIN725840
Quantity 100 μL
Reactivity Human
Application IF, IHC (p), WB
Validations
  • collections(3)
Cat. No. ABIN392217
Quantity 400 μL

Recommended IRS2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • collections(1)
Cat. No. ABIN6956772
Quantity 96 tests
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • collections(1)
Cat. No. ABIN6967616
Quantity 96 tests
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • collections(1)
Cat. No. ABIN6956770
Quantity 96 tests

Recommended IRS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • collections(1)
Cat. No. ABIN3093121
Quantity 1 mg
Reactivity Mouse
Source Insect Cells
Validations
  • collections(1)
Cat. No. ABIN3134673
Quantity 1 mg
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • collections(1)
Cat. No. ABIN6238418
Quantity 50 μg

Latest Publications on our IRS2 Products

Głombik, Ślusarczyk, Trojan, Chamera, Budziszewska, Lasoń, Basta-Kaim: "Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 27, Issue 2, pp. 120-131, (2017) (PubMed).

Wang, Wang, Zhang, Lin, Liu, Xiao, Xiao, Wang: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).

Ling, Xie, Li, Liu, Cao, Yang, Wang, Hu, Xu, Zheng: "Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 17, Issue 1, pp. 255-264, (2016) (PubMed).

Liu, You, Weng, Wei, Eng, Huang: "Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145388, (2015) (PubMed).

Dearth, Cui, Kim, Hadsell, Lee: "Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2." in: Cell cycle (Georgetown, Tex.), Vol. 6, Issue 6, pp. 705-13, (2007) (PubMed).

Li, Soos, Li, Wu, Degennaro, Sun, Littman, Birnbaum, Polakiewicz: "Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45304-7, (2004) (PubMed).

White: "IRS proteins and the common path to diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 283, Issue 3, pp. E413-22, (2002) (PubMed).

Burks, White: "IRS proteins and beta-cell function." in: Diabetes, Vol. 50 Suppl 1, pp. S140-5, (2001) (PubMed).

Synonyms and alternative names related to IRS2

insulin receptor substrate 2 (IRS2), insulin receptor substrate 2a (irs2a), insulin receptor substrate 2b (irs2b), insulin receptor substrate 2 (Irs2), 4PS, IRS-2, Irs-2, IRS2, si:dkeyp-24d6.1

Protein level used designations for IRS2

  • insulin receptor substrate 2
  • tyrosine kinase substrate
  • 4PS
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