(4 references)-
- 抗原 See all IRF3 蛋白
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 小麦胚
- 标记
- This IRF3 protein is labelled with GST tag.
- 应用范围
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- 原理
- IRF3 (Human) Recombinant Protein (P01)
- 序列
- MGTPKPRILP WLVSQLDLGQ LEGVAWVNKS RTRFRIPWKH GLRQDAQQED FGIFQAWAEA TGAYVPGRDK PDLPTWKRNF RSALSRKEGL RLAEDRSKDP HDPHKIYEFV NSGVGDFSQP DTSPDTNGGG STSDTQEDIL DELLGNMVLA PLPDPGPPSL AVAPEPCPQP LRSPSLDNPT PFPNLGPSEN PLKRLLVPGE EWEFEVTAFY RGRQVFQQTI SCPEGLRLVG SEVGDRTLPG WPVTLPDPGM SLTDRGVMSY VRHVLSCLGG GLALWRAGQW LWAQRLGHCH TYWAVSEELL PNSGHGPDGE VPKGKEGGVF DLGPFIVGSW APRSDYLHGR KRTLTTLCPL VLCGGVMAPG PAVDQEARDG QGCAHVPQGL GRNGPGRGCL LPGEYCGPAH FQQPPTLPHL RPVQGLPAGL GGGHGFPGPW GDLSPRSSWC ASNPPVPHHL NQ
- 产品特性
- Human IRF3 full-length ORF ( AAH09395, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.
- 纯化方法
- in vitro wheat germ expression system
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Interferon Regulatory Factor 3 (IRF3) (AA 2-427) protein (His tag)
IRF3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interferon Regulatory Factor 3 (IRF3) (AA 1-427) protein (GST tag)IRF3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 3 (IRF3) (AA 1-419) protein (Strep Tag)Crystallography grade IRF3 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interferon Regulatory Factor 3 (IRF3) (AA 1-427) protein (Strep Tag)Crystallography grade IRF3 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interferon Regulatory Factor 3 (IRF3) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)IRF3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -80 °C
- 储存方法
- Best use within three months from the date of receipt of this protein.
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: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." in: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
: "Quantitation of the dynamic profiles of the innate immune response using multiplex selected reaction monitoring-mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1513-29, (2013) (PubMed).
: "NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses." in: PLoS ONE, Vol. 7, Issue 9, pp. e43756, (2012) (PubMed).
: "Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16202-9, (2009) (PubMed).
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: "The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing." in: BMC biology, Vol. 14, pp. 69, (2016) (PubMed).
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- 抗原
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- 别名
- IRF3 (IRF3 产品)
- 别名
- irf3 Protein, IRF3 Protein, C920001K05Rik Protein, IRF-3 Protein, interferon regulatory factor 3 Protein, interferon regulatory factor 7 Protein, irf3 Protein, IRF3 Protein, irf-3 Protein, Irf3 Protein, IRF7 Protein
- 背景
- Gene: interferon regulatory factor 3
- 基因ID
- 3661
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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