-
- 抗原 See all AKT3 抗体
- AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This AKT3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of Akt3 expressed in E. coli.
- 克隆位点
- 3B12F3F10
- Top Product
- Discover our top product AKT3 Primary Antibody
-
-
- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
-
-
Role for Akt3/protein kinase Bgamma in attainment of normal brain size." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1869-78, (2005) (PubMed).
: "Deregulated Akt3 activity promotes development of malignant melanoma." in: Cancer research, Vol. 64, Issue 19, pp. 7002-10, (2004) (PubMed).
: "
-
Role for Akt3/protein kinase Bgamma in attainment of normal brain size." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1869-78, (2005) (PubMed).
-
- 抗原
- AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
- 别名
- Akt3 (AKT3 产品)
- 别名
- MPPH antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, AI851531 antibody, D930002M15Rik antibody, Nmf350 antibody, Pkbg antibody, AKT serine/threonine kinase 3 antibody, thymoma viral proto-oncogene 3 antibody, v-akt murine thymoma viral oncogene homolog 3b antibody, AKT3 antibody, Akt3 antibody, akt3b antibody
- 背景
-
Description: Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53 kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
Aliases: Akt3
- 基因ID
- 10000
- HGNC
- 10000
- 途径
- PI3K-Akt Signaling, RTK signaling, TLR signaling, Hepatitis C, VEGF Signaling
-