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AKT3 产品

(V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))

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The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured AKT3 Categories

AKT3 抗体

High quality antibodies with extensive validation data.

AKT3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

AKT3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AKT3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN1043749
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (10)
Cat. No. ABIN564308
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, FACS, FM
Validations
  • (6)
Cat. No. ABIN5596898
Quantity 50 μg
Datasheet Datasheet

Recommended AKT3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971096
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971095
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960413
Quantity 96 tests
Datasheet Datasheet

Recommended AKT3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (3)
Cat. No. ABIN5624572
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569763
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344789
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AKT3 Products

Riquelme, Behrens, Lin, Simon, Papadimitrakopoulou, Izzo, Moran, Kalhor, Lee, Minna, Wistuba: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." in: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).

Liu, Huang, Ren, Wen, Liu, Yang, Wang, Zhu, Zeng, Feng, Zhang, Chen, Jia, Zhang, Xia, Chen: "Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-?B and PI3K/Akt3 signaling pathways." in: Scientific reports, Vol. 5, pp. 11614, (2015) (PubMed).

Yang, Xiong, Luo, Yang, Xi: "8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 37, Issue 1, pp. 361-74, (2015) (PubMed).

OHurley, Daly, OGrady, Cummins, Quinn, Flanagan, Pierce, Fan, Lynn, Rafferty, Fitzgerald, Pontén, Duffy, Jirström, Kay, Gallagher: "Investigation of molecular alterations of AKT-3 in triple-negative breast cancer." in: Histopathology, Vol. 64, Issue 5, pp. 660-70, (2014) (PubMed).

Li, Jia, Ren, Liu, Gong, Wang, Zhang, Zhao: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).

Veillette, Grenier, Brasseur, Fréchette-Frigon, Leblanc, Parent, Asselin: "Regulation of the PI3-K/Akt survival pathway in the rat endometrium." in: Biology of reproduction, Vol. 88, Issue 3, pp. 79, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Vredeveld, Possik, Smit, Meissl, Michaloglou, Horlings, Ajouaou, Kortman, Dankort, McMahon, Mooi, Peeper: "Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis." in: Genes & development, Vol. 26, Issue 10, pp. 1055-69, (2012) (PubMed).

Bogen, Jensen, Hvalby, Walaas: "Glutamatergic neurotransmission in the synapsin I and II double knock-out mouse." in: Seminars in cell & developmental biology, Vol. 22, Issue 4, pp. 400-7, (2011) (PubMed).

Huang, Gonzalez, Toy, Banerjee, Kleer: "Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells." in: Cancer research, Vol. 70, Issue 8, pp. 3340-50, (2010) (PubMed).

Synonyms and alternative names related to AKT3

AKT serine/threonine kinase 3 (AKT3), thymoma viral proto-oncogene 3 (Akt3), AKT serine/threonine kinase 3 (Akt3), v-akt murine thymoma viral oncogene homolog 3b (akt3b), AI851531, D930002M15Rik, MPPH, Nmf350, PKB-GAMMA, PKBG, Pkbg, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2

Protein level used designations for AKT3

  • PKB gamma
  • RAC-gamma serine/threonine protein kinase
  • RAC-gamma serine/threonine-protein kinase
  • v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • RAC-PK-gamma
  • protein kinase Akt-3
  • protein kinase B gamma
  • AKT3 kinase
  • protein kinase B, gamma
  • thymoma viral proto-oncogene 3
  • v-akt murine thymoma viral oncogene 3
  • protein kinase B gamma-like protein
  • v-akt murine thymoma viral oncogene-like 3
  • LOW QUALITY PROTEIN: RAC-gamma serine/threonine-protein kinase
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