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ALAS2 产品

(Aminolevulinate, delta-, Synthase 2 (ALAS2))

Categories

The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured ALAS2 Categories

ALAS2 抗体

High quality antibodies with extensive validation data.

ALAS2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ALAS2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ALAS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (4)
Cat. No. ABIN559841
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2854459
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7142596
Quantity 100 μg
Datasheet Datasheet

Recommended ALAS2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1742701
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1773605
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1771157
Quantity 96 tests
Datasheet Datasheet

Recommended ALAS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344799
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1989568
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN3081409
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ALAS2 Products

Sawicki, Shang, Wu, Chang, Khechaduri, Sato, Kamide, Liu, Naga Prasad, Ardehali: "Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury." in: Journal of the American Heart Association, Vol. 4, Issue 8, pp. e002272, (2015) (PubMed).

Egan, Yang, Phillips, Abkowitz: "Inducing iron deficiency improves erythropoiesis and photosensitivity in congenital erythropoietic porphyria." in: Blood, Vol. 126, Issue 2, pp. 257-61, (2015) (PubMed).

Vercellotti, Khan, Nguyen, Chen, Bruzzone, Bechtel, Brown, Nath, Steer, Hebbel, Belcher: "H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice." in: Frontiers in pharmacology, Vol. 5, pp. 79, (2014) (PubMed).

Ma, Chen, Wu, Zhao, Yu, Yu, Zhang: "Emodin can induce K562 cells to erythroid differentiation and improve the expression of globin genes." in: Molecular and cellular biochemistry, Vol. 382, Issue 1-2, pp. 127-36, (2013) (PubMed).

Zhang, Shen, Liu, Wang, Zhao, Yu, Zhang: "Hypoxic induction of human erythroid-specific ?-aminolevulinate synthase mediated by hypoxia-inducible factor 1." in: Biochemistry, Vol. 50, Issue 7, pp. 1194-202, (2011) (PubMed).

Chien, Chang, Lee, Su, Wu: "Non-genomic immunosuppressive actions of progesterone inhibits PHA-induced alkalinization and activation in T cells." in: Journal of cellular biochemistry, Vol. 99, Issue 1, pp. 292-304, (2006) (PubMed).

Synonyms and alternative names related to ALAS2

5'-aminolevulinate synthase 2 (alas2), 5'-aminolevulinate synthase 2 (ALAS2), 5'-aminolevulinate synthase 2 (Alas2), 5'-aminolevulinate synthase 2 (alas2.L), aminolevulinate, delta-, synthase 2 (alas2), aminolevulinic acid synthase 2, erythroid (Alas2), ALAS, Alas-2, ALAS-E, alas-e, ALASE, anh1, ANH1, asb, ASB, cb1063, sau, sauternes, XLDPP, XLEPP, xlsa, XLSA

Protein level used designations for ALAS2

  • 5-aminolevulinate synthase 2
  • aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)
  • 5-aminolevulinate synthase, erythroid-specific, mitochondrial
  • aminolevulinate, delta-, synthase 2
  • ALAS-E
  • delta-ALA synthase 2
  • 5-aminolevulinic acid synthase 2
  • delta-aminolevulinate synthase 2
  • 5-aminolevulinate synthase, erythroid-specific, mitochondrial-like
  • delta-ALA synthetase
  • delta-ALA synthetase 2
  • Aminolevulinate synthase 2, delta
  • aminolevulinic acid synthase 2, erythroid
  • erythroid-specific delta-aminolevulinate synthase ALAS-E
  • erythroid aminolevulinate synthase
  • erythroid-specific ALAS
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