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C-JUN 抗体 (AA 26-175)

Name: C-JUN 抗体 (AA 26-175)
SKU: ABIN967903
Availability: OutOfStock

This anti-C-JUN antibody is a 小鼠单克隆 antibody detecting C-JUN in WB, IHC, IP 和 IF. Suitable for 人, 小鼠, 大鼠, 小鸡和犬. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of Jun on human endothelial cell lysate. (C-JUN 抗体 (AA 26-175))

Immunohistochemical staining of rat brain. (C-JUN 抗体 (AA 26-175))

IHC (p)

Immunohistochemical staining of Rabbit Muscle tissue section. (C-JUN 抗体 (AA 26-175))

IHC (p)

3 images

(5 references)

产品编号 ABIN967903

发货至: 中国

Datasheet as PDF

Quick Overview for C-JUN 抗体 (AA 26-175) (ABIN967903)

抗原

See all C-JUN (JUN) 抗体

C-JUN (JUN) (Jun Proto-Oncogene (JUN))

适用

人, 小鼠, 大鼠, 小鸡, 犬

宿主

小鼠

克隆类型

单克隆

标记

This C-JUN antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

3-Jun

Discover our top product JUN Primary Antibody

抗原表位
46

43

38

28

20

16

16

15

9

8

7

7

7

7

5

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 26-175

交叉反应

人, 小鸡, 犬, 大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Mouse c-Jun aa. 26-175

亚型

IgG2a
anti-Jun Proto-Oncogene (JUN) (AA 31-331) antibody
JUN 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibody
JUN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B1 unconjugated

anti-Jun Proto-Oncogene (JUN) (pThr91) antibody
JUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibody
JUN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) (N-Term) antibody
JUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated

anti-Jun Proto-Oncogene (JUN) (pSer73) antibody
JUN 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9F5 unconjugated

anti-Jun Proto-Oncogene (JUN) antibody
JUN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal 4A11 unconjugated

说明

Related Products: ABIN968536, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Doray, Ghosh, Griffith, Geuze, Kornfeld: "Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network." in: Science (New York, N.Y.), Vol. 297, Issue 5587, pp. 1700-3, (2002) (PubMed).

He, Stepulak, Holmström, Omary, Eriksson: "The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase." in: The Journal of biological chemistry, Vol. 277, Issue 13, pp. 10767-74, (2002) (PubMed).

Chang, Nakajima, Illenye, Lee, Honjo, Makiyama, Fujiwara, Mizuta, Sawai, Saida, Mitsui, Heintz, Magae: "Caspase-dependent apoptosis by ectopic expression of E2F-4." in: Oncogene, Vol. 19, Issue 41, pp. 4713-20, (2000) (PubMed).

Taupin, Wu, Jeon, Devaney, Wang, Podolsky: "The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation." in: The Journal of clinical investigation, Vol. 103, Issue 9, pp. R31-8, (1999) (PubMed).

Lamph, Wamsley, Sassone-Corsi, Verma: "Induction of proto-oncogene JUN/AP-1 by serum and TPA." in: Nature, Vol. 334, Issue 6183, pp. 629-31, (1988) (PubMed).
抗原

C-JUN (JUN) (Jun Proto-Oncogene (JUN))

别名

Jun

背景

The activator protein transcription factor (AP-1) was identified as a protein that recognizes specific sequences in the cis-control regions of the SV40 virus and the human metallothionein IIA gene. AP-1 is composed of protein products of two different gene families: jun and fos. The AP-1 transcription factor is either a homodimer of Jun proteins or a heterodimer of Jun and Fos proteins. The transcriptional activity of Jun is enhanced by phosphorylation in its activation domain at Ser63 and Ser73. Phosphorylation at both sites is necessary for stimulating the activating function of Jun. Jun is phosphorylated by JNK protein kinases that are activated by the same signals that potentiate Jun activity. This antibody is routinely tested by western blot analysis.

分子量

39 kDa

途径

MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins