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AKT3 抗体

AKT3 适用: 人 WB, ELISA Monoclonal unconjugated
产品编号 ABIN965532
发货至: 中国
  • 抗原 See all AKT3 抗体
    AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
    适用
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    克隆类型
    • 75
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    单克隆
    标记
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    This AKT3 antibody is un-conjugated
    应用范围
    • 88
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    Western Blotting (WB), ELISA
    特异性
    Ni-NTA purified truncated recombinant Akt3 expressed in E. Coli strain BL21 (DE3)
    纯化方法
    Crude ascites.
    Top Product
    Discover our top product AKT3 Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 2000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C
  • Easton, Cho, Roovers, Shineman, Mizrahi, Forman, Lee, Szabolcs, de Jong, Oltersdorf, Ludwig, Efstratiadis, Birnbaum: "Role for Akt3/protein kinase Bgamma in attainment of normal brain size." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1869-78, (2005) (PubMed).

    Stahl, Sharma, Cheung, Zimmerman, Cheng, Bosenberg, Kester, Sandirasegarane, Robertson: "Deregulated Akt3 activity promotes development of malignant melanoma." in: Cancer research, Vol. 64, Issue 19, pp. 7002-10, (2004) (PubMed).

  • 抗原
    AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
    别名
    Akt3 (AKT3 产品)
    别名
    MPPH antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, AI851531 antibody, D930002M15Rik antibody, Nmf350 antibody, Pkbg antibody, AKT serine/threonine kinase 3 antibody, thymoma viral proto-oncogene 3 antibody, v-akt murine thymoma viral oncogene homolog 3b antibody, AKT3 antibody, Akt3 antibody, akt3b antibody
    背景
    Akt3 (also designated protein kinase B gamma or vakt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
    基因ID
    10000
    途径
    PI3K-Akt Signaling, RTK signaling, TLR signaling, Hepatitis C, VEGF Signaling
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