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C-JUN 抗体 (pTyr170) (AbBy Fluor® 555)

This AbBy Fluor® 555-conjugated 兔 多克隆 anti-C-JUN antibody specifically detects C-JUN in WB, FACS 和 IF (cc). The antibody is reactive with 人 samples.
产品编号 ABIN879105
发货至: 中国
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Quick Overview for C-JUN 抗体 (pTyr170) (AbBy Fluor® 555) (ABIN879105)

抗原

See all C-JUN (JUN) 抗体
C-JUN (JUN) (Jun Proto-Oncogene (JUN))

适用

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宿主

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克隆类型

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多克隆

标记

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This C-JUN antibody is conjugated to AbBy Fluor® 555

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
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    pTyr170

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Tyr170

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    C-JUN (JUN) (Jun Proto-Oncogene (JUN))

    别名

    c-Jun

    背景

    Synonyms: c-Jun phospho Y170, p-c-Jun phospho Y170, c-Jun Tyr170, Jun oncogene, JUN, Activator Protein 1, AP 1, AP1, AP-1, Enhancer Binding Protein AP1, Jun Activation Domain Binding Protein, JUN protein, JUNC, p39, Proto oncogene cJun, Transcription Factor AP1, V jun avian sarcoma virus 17 oncogene homolog, vJun Avian Sarcoma Virus 17 Oncogene Homolog, JUN_HUMAN, Transcription factor AP-1, Activator 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog.

    Background: The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

    基因ID

    3725

    途径

    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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