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ITK 抗体 (AA 596-607)

ITK 适用: 人 IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN783291
发货至: 中国
  • 抗原 See all ITK 抗体
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    抗原表位
    • 14
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 596-607
    适用
    • 51
    • 19
    • 12
    • 6
    • 3
    宿主
    • 63
    • 5
    • 2
    山羊
    克隆类型
    • 64
    • 6
    多克隆
    标记
    • 31
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITK antibody is un-conjugated
    应用范围
    • 43
    • 37
    • 14
    • 14
    • 12
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to Interleukin 2 Tyrosine Kinase (ITK).
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide C-KERPEDRPAFSR from positions 596-607 of human ITK (NP_005537.3). Genename: ITK
    亚型
    IgG
    Top Product
    Discover our top product ITK Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    别名
    Tyrosine-Protein Kinase ITK/TSK (ITK 产品)
    别名
    Emt antibody, Tcsk antibody, Tsk antibody, EMT antibody, LPFS1 antibody, LYK antibody, PSCTK2 antibody, IL2 inducible T cell kinase antibody, IL2 inducible T-cell kinase antibody, IL2-inducible T-cell kinase antibody, Itk antibody, ITK antibody
    背景
    Interleukin-2 tyrosine kinase (ITK), a BTK/TEC type tyrosine kinase, is critical for efficient signaling downstream of the T cell receptor. Itk is directly phosphorylated and activated by Lck. Subsequently, Itk activates phospholipase C-gamma1, leading to calcium mobilization and extracellular signal-regulated kinase/mitogen-activated protein kinase activation. Itk contains five domains in addition to the catalytic domain: pleckstrin homology, Tec homology which contains a proline-rich region, Src homology 3, and Src homology 2.Synonyms: EMT, Kinase EMT, LYK, T-cell-specific kinase, Tyrosine-protein kinase Lyk
    基因ID
    3702
    NCBI登录号
    NP_005537
    UniProt
    Q08881
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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