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ITK 抗体

ITK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5G6 unconjugated
产品编号 ABIN969222
发货至: 中国
  • 抗原 See all ITK 抗体
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    适用
    • 48
    • 19
    • 12
    • 6
    • 3
    宿主
    • 62
    • 3
    • 2
    小鼠
    克隆类型
    • 64
    • 3
    单克隆
    标记
    • 28
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    • 3
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ITK antibody is un-conjugated
    应用范围
    • 40
    • 35
    • 14
    • 14
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human ITK expressed in E. coli.
    克隆位点
    5G6
    亚型
    IgG1
    Top Product
    Discover our top product ITK Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

    Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).

  • 抗原
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    别名
    ITK (ITK 产品)
    别名
    Emt antibody, Tcsk antibody, Tsk antibody, EMT antibody, LPFS1 antibody, LYK antibody, PSCTK2 antibody, IL2 inducible T cell kinase antibody, IL2 inducible T-cell kinase antibody, IL2-inducible T-cell kinase antibody, Itk antibody, ITK antibody
    背景

    Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    Aliases: EMT, LYK, PSCTK2, MGC126257, MGC126258

    分子量
    72 kDa
    基因ID
    3702
    HGNC
    3702
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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