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PTPN11 抗体 (pTyr584) (FITC)

PTPN11 适用: 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN745845
发货至: 中国
  • 抗原 See all PTPN11 抗体
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    抗原表位
    • 32
    • 25
    • 15
    • 14
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr584
    适用
    • 154
    • 115
    • 104
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    小鼠, 大鼠
    宿主
    • 168
    • 14
    • 2
    • 1
    克隆类型
    • 148
    • 37
    多克隆
    标记
    • 88
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PTPN11 antibody is conjugated to FITC
    应用范围
    • 120
    • 50
    • 42
    • 26
    • 26
    • 25
    • 20
    • 16
    • 14
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    特异性
    This phosphorylation site is homologous across the listed cross reactive species.
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584
    亚型
    IgG
    Top Product
    Discover our top product PTPN11 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    别名
    PTPN11 (PTPN11 产品)
    别名
    BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
    物质类
    Viral Protein
    背景

    Synonyms: CFC, NS1, SHP2, BPTP3, PTP2C, PTP-1D, SH-PTP2, SH-PTP3, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, PTP-2C, SHP-2, PTPN11, SHPTP2

    Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.

    基因ID
    5781
    UniProt
    Q06124
    途径
    JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
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