PTPN11 抗体 (C-Term)
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- 抗原 See all PTPN11 抗体
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to SHP2 (protein tyrosine phosphatase, non-receptor type 11)
SHP2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human SHP2. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 263-329) antibody
PTPN11 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D9 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 514-593) antibodyPTPN11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyVerified PTPN11 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibodyPTPN11 适用: 人 WB, IHC, ELISA, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 6D9 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 501-597) antibodyPTPN11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibodyPTPN11 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr542) antibodyPTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr580) antibodyPTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibodyPTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibodyPTPN11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21493 unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: rat brain , Mouse brain
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.63 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
- 别名
- protein tyrosine phosphatase non-receptor type 11 (PTPN11 产品)
- 别名
- BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
- 物质类
- Viral Protein
- 背景
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Cellular Localization: Cytoplasm - 分子量
- 68 kDa
- 基因ID
- 5781
- UniProt
- Q06124
- 途径
- JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
