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PTPN11 抗体

(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
PTPN11 抗体  (AA 514-593) PTPN11 抗体  (AA 514-593) PTPN11 抗体 (AA 514-593) (ABIN3016707)

PTPN11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

PTPN11 抗体  (AA 263-329) PTPN11 抗体  (AA 263-329) PTPN11 抗体 (AA 263-329) (ABIN1098117)

PTPN11 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D9 unconjugated

PTPN11 抗体  (C-Term) PTPN11 抗体  (C-Term) PTPN11 抗体 (C-Term) (ABIN184604)

Verified PTPN11 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

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Find PTPN11 抗体 for a variety of species such as anti-Human PTPN11, anti-Mouse PTPN11, anti-Rat PTPN11. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find PTPN11 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PTPN11 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN3016707
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (2)
  • (6)
Cat. No. ABIN1098117
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, FACS
Validations
  • (6)
Cat. No. ABIN184604
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IHC (p), IF, FACS
Validations
  • (6)
Cat. No. ABIN1491299
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN2854914
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (1)
  • (3)
Cat. No. ABIN6243732
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (1)
  • (3)
Cat. No. ABIN519514
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog, Human
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN1500499
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7260659
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6265075
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256769
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256761
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN7269704
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN3032394
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (3)
Cat. No. ABIN6146440
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PTPN11 抗体

Ganesan, Rasool: "Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).

Yan, Zhou, Chen, Li, Yang, You, Ling: "Effects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells." in: Journal of Cancer, Vol. 6, Issue 2, pp. 151-9, (2015) (PubMed).

Chang, Gao, Han, Du, Liu, Wang, Tan, Zhang, Liu, Zhu, Yu, Fan, Zhang, Zhou, Wang, Fu, Cao: "Gene expression profiling-derived immunohistochemistry signature with high prognostic value in colorectal carcinoma." in: Gut, Vol. 63, Issue 9, pp. 1457-67, (2014) (PubMed).

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Li, Modi, McDonald, Rossi, Yee, Bhatia: "A critical role for SHP2 in STAT5 activation and growth factor-mediated proliferation, survival, and differentiation of human CD34+ cells." in: Blood, Vol. 118, Issue 6, pp. 1504-15, (2011) (PubMed).

Bard-Chapeau, Li, Ding, Zhang, Zhu, Princen, Fang, Han, Bailly-Maitre, Poli, Varki, Wang, Feng: "Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis." in: Cancer cell, Vol. 19, Issue 5, pp. 629-39, (2011) (PubMed).

Yao, Zhu, Zhao, Liu, Luo, Yin: "Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway." in: Journal of cellular biochemistry, Vol. 112, Issue 10, pp. 2837-49, (2011) (PubMed).

Carver, Piazza, Schuler: "Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8003-12, (2010) (PubMed).

Rani, Dhandapany, Nallari, Govindaraj, Singh, Thangaraj: "Mitochondrial DNA haplogroup 'R' is associated with Noonan syndrome of south India." in: Mitochondrion, Vol. 10, Issue 2, pp. 166-73, (2010) (PubMed).

Bakken, He, Cannon: "The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells." in: Virology, Vol. 397, Issue 2, pp. 379-88, (2010) (PubMed).

Aliases for PTPN11 抗体

protein tyrosine phosphatase, non-receptor type 11 (PTPN11) 抗体
protein tyrosine phosphatase, non-receptor type 11 (Ptpn11) 抗体
protein tyrosine phosphatase, non-receptor type 11 S homeolog (ptpn11.S) 抗体
protein tyrosine phosphatase, non-receptor type 11, a (ptpn11a) 抗体
protein tyrosine phosphatase, non-receptor type 11, b (ptpn11b) 抗体
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ptp-2 抗体
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PTP2C 抗体
ptp2c 抗体
ptpn11 抗体
ptpn11-a 抗体
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SH-PTP3 抗体
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