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PTPN11 抗体 (AA 526-551)

Name: PTPN11 抗体 (AA 526-551)
SKU: ABIN3032394
Availability: OutOfStock

PTPN11 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

Western blot analysis of SHP2 antibody and 1) 293, 2) K562 lysate. (PTPN11 抗体 (AA 526-551))

Flow cytometric analysis of 293 cells using SHP2 antibody (green) compared to a negative control (blue). (PTPN11 抗体 (AA 526-551))

FACS

IHC analysis of FFPE human hepatocarcinoma stained with SHP2 antibody (PTPN11 抗体 (AA 526-551))

IHC

Flow cytometric analysis of 293 cells using SHP2 antibody (green) compared to a (PTPN11 抗体 (AA 526-551))

FACS

5 images

产品编号 ABIN3032394

发货至: 中国

Datasheet as PDF

抗原 See all PTPN11 抗体

PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
抗原表位
32

25

15

15

9

7

7

6

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 526-551
适用
153

116

105

10

10

9

8

8

8

7

5

5

4

3

1
人
宿主
168

14

2

1
兔
Compatible Secondaries
克隆类型
148

37
多克隆
标记
87

12

9

9

9

9

9

9

7

5

3

3

2

2

2

2

2

2

2
This PTPN11 antibody is un-conjugated
应用范围
120

49

41

27

26

26

20

15

14

7

6

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

交叉反应（详细）

Expected species reactivity: Mouse, Rat, Chicken

纯化方法

Antigen affinity

免疫原

A portion of amino acids 526-551 from the human protein was used as the immunogen for this SHP2 antibody.

亚型

Ig Fraction

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PTPN11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 263-329) antibody
PTPN11 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D9 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
Verified PTPN11 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibody
PTPN11 适用: 人 WB, IHC, ELISA, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 6D9 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
KO Validated PTPN11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 526-551) antibody
PTPN11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21493 unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) antibody
PTPN11 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (AA 1-460) antibody
PTPN11 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (C-Term) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr580) antibody
PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the SHP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the SHP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

别名

SHP2 (PTPN11 产品)

别名

BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody

物质类

Viral Protein

背景

SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in the gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

UniProt

Q06124

途径

JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect