PTPN2 抗体
(Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| PTPN2 抗体 | 大鼠, 小鼠 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 1-353) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 1-257) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 1-387) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 201-250) | 人, 大鼠, 小鼠, 豚鼠, 马, 兔, 犬, Cow, 斑马鱼, 小鸡, 猴, 非洲爪蟾 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 23-72) | 人, 大鼠, 小鼠, 豚鼠, 马, 兔, Cow, 斑马鱼, 小鸡, 猴 | 兔 Polyclonal |
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| PTPN2 抗体 (N-Term) | 人, 大鼠, 小鼠, 犬 | 兔 Polyclonal |
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| PTPN2 抗体 (C-Term) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 1-50) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 1-387) | 人 | 小鼠 Polyclonal |
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| PTPN2 抗体 (AA 1-330) | 人, 大鼠 | 兔 Polyclonal |
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| PTPN2 抗体 | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 1-257) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 329-358) (APC) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 329-358) (Biotin) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 329-358) (HRP) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 329-358) (FITC) | 人 | 兔 Polyclonal |
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| PTPN2 抗体 (AA 329-358) (PE) | 人 | 兔 Polyclonal |
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Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-353
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
1 reference - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB33304
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 329-358, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-257
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-387
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 大鼠, 小鼠, 豚鼠, 马, 兔, 犬, Cow, 斑马鱼, 小鸡, 猴, 非洲爪蟾
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 201-250
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 大鼠, 小鼠, 犬
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-50
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-387
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-330
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-257
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 329-358
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 329-358
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 329-358
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 329-358
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 329-358
Latest Publications for our PTPN2 抗体
: "Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2), an Important Regulator of IL-6 Production in Rheumatoid Arthritis Synovial Fibroblasts." in: Arthritis & rheumatology (Hoboken, N.J.), (2015) (PubMed).
: "T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease." in: Immunological reviews, Vol. 228, Issue 1, pp. 325-41, (2009) (PubMed).
: "TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}." in: Blood, Vol. 109, Issue 10, pp. 4220-8, (2007) (PubMed).
: "Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP." in: Molecular and cellular biology, Vol. 23, Issue 6, pp. 2096-108, (2003) (PubMed).
: "Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 2, pp. 726-32, (2003) (PubMed).
: "Identification of a nuclear Stat1 protein tyrosine phosphatase." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5662-8, (2002) (PubMed).
: "T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease." in: Immunological reviews, Vol. 228, Issue 1, pp. 325-41, (2009) (PubMed).
: "TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}." in: Blood, Vol. 109, Issue 10, pp. 4220-8, (2007) (PubMed).
: "Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP." in: Molecular and cellular biology, Vol. 23, Issue 6, pp. 2096-108, (2003) (PubMed).
: "Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 2, pp. 726-32, (2003) (PubMed).
: "Identification of a nuclear Stat1 protein tyrosine phosphatase." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5662-8, (2002) (PubMed).
Aliases for PTPN2 抗体
protein tyrosine phosphatase, non-receptor type 2 (PTPN2) 抗体protein tyrosine phosphatase, non-receptor type 2 (Ptpn2) 抗体
protein tyrosine phosphatase, non-receptor type 2 S homeolog (ptpn2.S) 抗体
protein tyrosine phosphatase, non-receptor type 2, b (ptpn2b) 抗体
protein tyrosine phosphatase, non-receptor type 2, a (ptpn2a) 抗体
protein tyrosine phosphatase, non-receptor type 2 L homeolog (ptpn2.L) 抗体
AI325124 抗体
cb806 抗体
hm:zeh1546 抗体
PTN2 抗体
ptn2 抗体
PTP-1B 抗体
ptpn2 抗体
ptpn2l 抗体
PTPT 抗体
Ptpt 抗体
ptpt 抗体
TC-PTP 抗体
tc-ptp 抗体
TCELLPTP 抗体
tcellptp 抗体
TCPTP 抗体
tcptp 抗体
wu:fc10h07 抗体
zgc:55339 抗体
zgc:63623 抗体
zgc:76973 抗体
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