PTPRF 抗体
(Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
recommended
recommended
PTPRF 适用: 人 WB, ELISA, ICC, FACS, IHC, Neut 宿主: 小鼠 Monoclonal 6D7C7 unconjugated
recommended
PTPRF 抗体 by 适用
Find PTPRF 抗体 for a variety of species such as anti-Human PTPRF, anti-Mouse PTPRF, anti-Rat PTPRF. The species listed below are among those available. Click on a link to go to the corresponding products.
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PTPRF 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PTPRF 抗体. Click on a link to go to the corresponding products.
PTPRF 抗体 by 克隆
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Latest Publications for our PTPRF 抗体
: "A new 12-gene diagnostic biomarker signature of melanoma revealed by integrated microarray analysis." in: PeerJ, Vol. 1, pp. e49, (2013) (PubMed).: "Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses." in: Journal of cell science, Vol. 126, Issue Pt 21, pp. 4926-38, (2013) (PubMed).
: "Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47263-9, (2002) (PubMed).
: "Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule." in: Molecular cancer research : MCR, Vol. 1, Issue 2, pp. 155-63, (2002) (PubMed).
: "Galpha(i2) enhances insulin signaling via suppression of protein-tyrosine phosphatase 1B." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 39705-12, (2001) (PubMed).
: "Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 9, pp. 5187-92, (2001) (PubMed).
: "Use of an antisense strategy to dissect the signaling role of protein-tyrosine phosphatase alpha." in: The Journal of biological chemistry, Vol. 274, Issue 37, pp. 26105-12, (1999) (PubMed).
: "Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression." in: The Journal of biological chemistry, Vol. 268, Issue 35, pp. 26503-11, (1994) (PubMed).
: "The SJL/J T cell response to both spontaneous and transplantable syngeneic reticulum cell sarcoma is mediated predominantly by the V beta 17a+ T cell clonotype." in: The Journal of experimental medicine, Vol. 168, Issue 5, pp. 1553-62, (1988) (PubMed).
Aliases for PTPRF 抗体
protein tyrosine phosphatase, receptor type F (PTPRF) 抗体protein tyrosine phosphatase, receptor type, F (Ptprf) 抗体
protein tyrosine phosphatase, receptor type, f, a (ptprfa) 抗体
AA591035 抗体
LAR 抗体
LARFN5C 抗体
LARS 抗体
RPTP-LAR 抗体
zf-LAR 抗体
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