PTPRF 抗体 (AA 1104-1163)
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- 抗原 See all PTPRF 抗体
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
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抗原表位
- AA 1104-1163
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PTPRF antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human PTPRF (AA: extra 1104-1163) expressed in E. coli.
- 克隆位点
- 6D7C7
- 亚型
- IgG1
- Top Product
- Discover our top product PTPRF Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- 限制
- 仅限研究用
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- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
- 别名
- PTPRF (PTPRF 产品)
- 别名
- LAR antibody, AA591035 antibody, LARS antibody, RPTP-LAR antibody, LARFN5C antibody, zf-LAR antibody, protein tyrosine phosphatase, receptor type F antibody, protein tyrosine phosphatase, receptor type, F antibody, protein tyrosine phosphatase, receptor type, f, a antibody, PTPRF antibody, Ptprf antibody, ptprfa antibody
- 背景
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Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Aliases: LAR, BNAH2
- 分子量
- 213 kDa
- 基因ID
- 5792
- 途径
- EGFR Signaling Pathway
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