PTPRF 抗体 (AA 1315-1607) (Atto 488)
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- 抗原 See all PTPRF 抗体
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
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抗原表位
- AA 1315-1607
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PTPRF antibody is conjugated to Atto 488
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~85 kDa (full length protein is 210 kDa - smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR. 97% identical in both rat and mouse. >80% identity with PTPRD and PTPRS. >50% identity with PTPRM and PTPRK.
- 克隆位点
- S165-38
- 亚型
- IgG2a
- Top Product
- Discover our top product PTPRF Primary Antibody
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anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 30-224) antibody
PTPRF 适用: 人 WB, ICC, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1104-1163) antibodyPTPRF 适用: 人 WB, ELISA, ICC, FACS, IHC, Neut 宿主: 小鼠 Monoclonal 6D7C7 unconjugated
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 688-970) antibodyPTPRF 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibodyPTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 unconjugated
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibody (HRP)PTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 HRP
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibody (FITC)PTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 FITC
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibody (Biotin)PTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 Biotin
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibody (PE)PTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 PE
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibody (APC)PTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 APC
anti-Protein Tyrosine Phosphatase Receptor Type F (PTPRF) (AA 1315-1607) antibody (PerCP)PTPRF 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal S165-38 PerCP
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- 应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN1740983 was sufficient for detection of LAR/PTPRF in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))
- 别名
- LAR (PTPRF 产品)
- 别名
- LAR antibody, AA591035 antibody, LARS antibody, RPTP-LAR antibody, LARFN5C antibody, zf-LAR antibody, protein tyrosine phosphatase, receptor type F antibody, protein tyrosine phosphatase, receptor type, F antibody, protein tyrosine phosphatase, receptor type, f, a antibody, PTPRF antibody, Ptprf antibody, ptprfa antibody
- 背景
- PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from β-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide.
- 基因ID
- 5792
- UniProt
- P10586
- 途径
- EGFR Signaling Pathway
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