C-JUN 抗体 (pSer79)
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Quick Overview for C-JUN 抗体 (pSer79) (ABIN7232967)
抗原
See all C-JUN (JUN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer79
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原理
- Anti-c-Jun (Phospho-Ser79) Rabbit Polyclonal Antibody
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特异性
- This antibody detects endogenous human, mouse, and rat c-Jun only when phosphorylated at serine 79.
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交叉反应
- 人, 小鼠, 大鼠
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免疫原
- Peptide sequence that includes phosphorylation site of Serine 79 (G-A-S(p)-L-K) derived from human c-Jun and conjugated to KLH.
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应用备注
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Immunohistochemistry: use at dilution of 1:50- 1:100.
Immunofluorescence: use at dilution of 1:100- 1:200.
These are recommended working dilutions.
End user should determine optimal dilutions for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2 and Ca2 ), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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别名
- c-Jun
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背景
- C-Jun in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function
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途径
- MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
抗原
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