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Recombinant PTPN11 抗体 (pTyr542)

PTPN11 适用: 人 WB, ELISA, IP 宿主: 兔 Monoclonal 2E2 unconjugated Recombinant Antibody
产品编号 ABIN7127735
发货至: 中国
  • 抗原 See all PTPN11 抗体
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 30
    • 20
    • 15
    • 15
    • 9
    • 7
    • 7
    • 6
    • 3
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    • 1
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    pTyr542
    适用
    • 146
    • 116
    • 105
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    宿主
    • 162
    • 13
    • 2
    • 1
    克隆类型
    • 149
    • 29
    单克隆
    标记
    • 83
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
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    • 2
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    • 2
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    • 2
    This PTPN11 antibody is un-conjugated
    应用范围
    • 118
    • 49
    • 42
    • 27
    • 26
    • 26
    • 19
    • 11
    • 11
    • 6
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Phospho-PTPN11 (Y542)
    克隆位点
    2E2
    亚型
    IgG
    Top Product
    Discover our top product PTPN11 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IP:1:200-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    别名
    PTPN11 (PTPN11 产品)
    别名
    BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
    物质类
    Viral Protein
    背景

    Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).

    Aliases: Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3, PTPN11, PTP2C, SHPTP2

    UniProt
    Q06124
    途径
    JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
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