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CHEK1 抗体

This anti-CHEK1 antibody is a 小鼠 单克隆 antibody detecting CHEK1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112651
发货至: 中国

Quick Overview for CHEK1 抗体 (ABIN7112651)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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  • 113
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人, 小鼠, 大鼠

宿主

  • 194
  • 11
  • 5
  • 5
小鼠

克隆类型

  • 189
  • 27
单克隆

标记

  • 122
  • 11
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  • 4
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  • 4
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  • 3
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  • 3
This CHEK1 antibody is un-conjugated

应用范围

  • 164
  • 81
  • 54
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  • 10
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

9F10
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    CHK1 checkpoint homolog

    亚型

    IgG2a
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    Chk1

    背景

    Synonyms:CHEK1, Chk1 Background:HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa.

    分子量

    50 kDa

    基因ID

    1111

    UniProt

    O14757

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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