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- 抗原 See all NUDT1 抗体
- NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUDT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- This antibody ist KO validated.
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 质量等级
- KO Validated
- 免疫原
- Recombinant fusion protein of human NUDT1 (NP_945192.1).
- 亚型
- IgG
- Top Product
- Discover our top product NUDT1 Primary Antibody
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anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 49-82) antibody
NUDT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-156) antibodyNUDT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-179) antibodyNUDT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 72-191) antibodyNUDT1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-179) antibodyNUDT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (Internal Region) antibodyNUDT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (C-Term) antibodyNUDT1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) antibodyNUDT1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-156) antibodyNUDT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (C-Term) antibodyNUDT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
- 别名
- NUDT1 (NUDT1 产品)
- 别名
- mutT antibody, nudT1 antibody, MTH1 antibody, Mth1 antibody, 7,8-dihydro-8-oxoguanine triphosphatase antibody, nudix hydrolase 1 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 1 antibody, mth1 antibody, Tsp_07498 antibody, nudt1 antibody, 8odp antibody, NUDT1 antibody, Nudt1 antibody
- 背景
- Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.
- 分子量
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Observed_MW: 18 kDa
Calculated_MW: 17 kDa/19 kDa/20 kDa/22 kDa
- 基因ID
- 4521
- UniProt
- P36639
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