NUDT1 抗体 (Internal Region)
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- 抗原 See all NUDT1 抗体
- NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUDT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- NUDT1 Antibody detects endogenous levels of total NUDT1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NUDT1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NUDT1 Primary Antibody
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anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 49-82) antibody
NUDT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-156) antibodyNUDT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) antibodyKO Validated NUDT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-179) antibodyNUDT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 72-191) antibodyNUDT1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-179) antibodyNUDT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (C-Term) antibodyNUDT1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) antibodyNUDT1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (AA 1-156) antibodyNUDT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1) (C-Term) antibodyNUDT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
- 别名
- NUDT1 (NUDT1 产品)
- 别名
- mutT antibody, nudT1 antibody, MTH1 antibody, Mth1 antibody, 7,8-dihydro-8-oxoguanine triphosphatase antibody, nudix hydrolase 1 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 1 antibody, mth1 antibody, Tsp_07498 antibody, nudt1 antibody, 8odp antibody, NUDT1 antibody, Nudt1 antibody
- 背景
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Description: Antimutagenic (PubMed:8226881, PubMed:7713500, PubMed:10608900). Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools (PubMed:28679043). Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress (PubMed:12857738, PubMed:24695224, PubMed:24695225). Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions (PubMed:8226881, PubMed:10373420, PubMed:10608900, PubMed:11756418, PubMed:12857738, PubMed:16607562, PubMed:24695224, PubMed:24695225, PubMed:26999531, PubMed:28035004). Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP (PubMed:10373420, PubMed:11139615). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).
Gene: NUDT1
- 分子量
- 22kDa
- 基因ID
- 4521
- UniProt
- P36639
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