NUDT1 抗体
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant NUDT1 抗体 | 人 | 兔 Monoclonal |
|
|
|
| NUDT1 抗体 (AA 1-179) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 49-82) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 1-179) | 人 | 小鼠 Monoclonal |
|
|
|
| NUDT1 抗体 (AA 1-156) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 1-156) | 人 | 小鼠 Monoclonal |
|
|
|
| NUDT1 抗体 | 人 | 兔 Monoclonal |
|
|
|
| NUDT1 抗体 (AA 1-179) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 1-156) | 人 | 小鼠 Polyclonal |
|
|
|
| NUDT1 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 1-80) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 49-82) (Biotin) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 49-82) (HRP) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 49-82) (FITC) | 人 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
|
| NUDT1 抗体 (AA 1-156) | 人 | 小鼠 Monoclonal |
|
|
|
| NUDT1 抗体 (N-Term) | 人 | 兔 Polyclonal |
|
|
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB4060
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-179
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 49-82
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5F11
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 1-179
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-156
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AT3B3
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-156
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-179
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-156
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-80
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 49-82
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 49-82
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 49-82
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AT3B3
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-156
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Latest Publications for our NUDT1 抗体
: "The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress." in: Mutation research, Vol. 808, pp. 10-19, (2019) (PubMed).
: "The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia." in: BMC cancer, Vol. 18, Issue 1, pp. 1190, (2019) (PubMed).
: "Potent and specific MTH1 inhibitors targeting gastric cancer." in: Cell death & disease, Vol. 10, Issue 6, pp. 434, (2019) (PubMed).
: "Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue." in: DNA repair, pp. 102644, (2019) (PubMed).
: "Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. ..." in: Nature communications, Vol. 9, Issue 1, pp. 250, (2018) (PubMed).
: "Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway." in: Journal of lipid research, Vol. 59, Issue 5, pp. 830-842, (2018) (PubMed).
: "Validating the concept of mutational signatures with isogenic cell models." in: Nature communications, Vol. 9, Issue 1, pp. 1744, (2018) (PubMed).
: "hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia." in: Oncogenesis, Vol. 5, Issue 12, pp. e275, (2016) (PubMed).
: "Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma." in: International journal of hematology, Vol. 105, Issue 3, pp. 318-325, (2016) (PubMed).
: "MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways." in: Oncogene, Vol. 34, Issue 20, pp. 2586-96, (2015) (PubMed).
: "The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia." in: BMC cancer, Vol. 18, Issue 1, pp. 1190, (2019) (PubMed).
: "Potent and specific MTH1 inhibitors targeting gastric cancer." in: Cell death & disease, Vol. 10, Issue 6, pp. 434, (2019) (PubMed).
: "Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue." in: DNA repair, pp. 102644, (2019) (PubMed).
: "Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. ..." in: Nature communications, Vol. 9, Issue 1, pp. 250, (2018) (PubMed).
: "Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway." in: Journal of lipid research, Vol. 59, Issue 5, pp. 830-842, (2018) (PubMed).
: "Validating the concept of mutational signatures with isogenic cell models." in: Nature communications, Vol. 9, Issue 1, pp. 1744, (2018) (PubMed).
: "hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia." in: Oncogenesis, Vol. 5, Issue 12, pp. e275, (2016) (PubMed).
: "Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma." in: International journal of hematology, Vol. 105, Issue 3, pp. 318-325, (2016) (PubMed).
: "MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways." in: Oncogene, Vol. 34, Issue 20, pp. 2586-96, (2015) (PubMed).
Aliases for NUDT1 抗体
7,8-dihydro-8-oxoguanine triphosphatase (mth1) 抗体7,8-dihydro-8-oxoguanine triphosphatase (Tsp_07498) 抗体
nudix hydrolase 1 (nudt1) 抗体
7,8-dihydro-8-oxoguanine triphosphatase (8odp) 抗体
nudix hydrolase 1 (NUDT1) 抗体
nudix (nucleoside diphosphate linked moiety X)-type motif 1 (Nudt1) 抗体
nudix hydrolase 1 (Nudt1) 抗体
MTH1 抗体
Mth1 抗体
mutT 抗体
nudT1 抗体
您还需要查找其他产品吗？
- Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 4 抗体
- Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 3 抗体
- NudE Neurodevelopment Protein 1 抗体
- NUDCD3 抗体
- NUDCD2 抗体
- NUDC 抗体
- Nucleotide Binding Protein 1 抗体
- Nucleostemin 抗体
- Nucleosome Assembly Protein 1-Like 4 抗体
- Nucleosome Assembly Protein 1-Like 1 抗体
- Nucleoside Diphosphate Kinase 抗体
- Nucleolin 抗体
- Nucleolar Protein 6 抗体
- Nucleolar Protein 1 抗体
- Nucleolar and Spindle Associated Protein 1 抗体
- Nucleobindin 1 抗体
- Nuclear Transcription Factor Y, beta 抗体
- Nuclear RNA Export Factor 1 抗体
- Nuclear Receptor Subfamily 2, Group C, Member 1 抗体
- Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体
You are here:
