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Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

(Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3))
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) (AA 429-442), (AA 443-456) 抗体 Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) (AA 429-442), (AA 443-456) 抗体 Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) (AA 429-442), (AA 443-456) 抗体 (ABIN185294)

Verified NR1H2/3 适用: 人 ELISA, FACS, IF, WB 宿主: 山羊 Polyclonal unconjugated

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Popular Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, IF, WB
Validations
  • (4)
Cat. No. ABIN185294
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

Sharma, Gupta, Dahiya, Kumar, Vaiphei, Agnihotri: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).

Scoles, Xu, Wang, Tran, Taylor-Harding, Li, Karlan: "Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein." in: Gynecologic oncology, Vol. 116, Issue 1, pp. 109-16, (2009) (PubMed).

Tangirala, Bischoff, Joseph, Wagner, Walczak, Laffitte, Daige, Thomas, Heyman, Mangelsdorf, Wang, Lusis, Tontonoz, Schulman: "Identification of macrophage liver X receptors as inhibitors of atherosclerosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 18, pp. 11896-901, (2002) (PubMed).

Aliases for Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

nuclear receptor subfamily 1 group H member 3 (NR1H3) 抗体
LXR-a 抗体
LXRA 抗体
RLD-1 抗体
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