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Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

(Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3))
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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  • 抗原: Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN185294
Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) (AA 429-442), (AA 443-456) 抗体 NR1H2/3 · Primary Antibody 人 山羊 Polyclonal
  • FACS (Flow Cytometry: 有验证图片)
  • IF (Immunofluorescence: 有验证图片)
  • WB (Western Blotting: 有验证图片)
  • ELISA (ELISA: 所列应用)
  • 100 μg
  • 20 μg
发货至: 中国
Primary Antibody
  • FACS (Flow Cytometry: 有验证图片)
  • IF (Immunofluorescence: 有验证图片)
  • WB (Western Blotting: 有验证图片)
  • ELISA (ELISA: 所列应用)
质量等级
Verified
适用
人
宿主
山羊
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 429-442, AA 443-456
产品编号 ABIN185294

Latest Publications for our Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

Sharma, Gupta, Dahiya, Kumar, Vaiphei, Agnihotri: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).

Scoles, Xu, Wang, Tran, Taylor-Harding, Li, Karlan: "Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein." in: Gynecologic oncology, Vol. 116, Issue 1, pp. 109-16, (2009) (PubMed).

Tangirala, Bischoff, Joseph, Wagner, Walczak, Laffitte, Daige, Thomas, Heyman, Mangelsdorf, Wang, Lusis, Tontonoz, Schulman: "Identification of macrophage liver X receptors as inhibitors of atherosclerosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 18, pp. 11896-901, (2002) (PubMed).

Aliases for Nuclear Receptor Subfamily 1, Group H, Member 2/3 抗体

nuclear receptor subfamily 1 group H member 3 (NR1H3) 抗体
LXR-a 抗体
LXRA 抗体
RLD-1 抗体
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