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NUDT1 抗体

NUDT1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7101592
发货至: 中国
  • 抗原 See all NUDT1 抗体
    NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
    适用
    • 29
    • 13
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    • 1
    • 1
    • 1
    • 1
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    宿主
    • 26
    • 3
    克隆类型
    • 26
    • 3
    单克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    This NUDT1 antibody is un-conjugated
    应用范围
    • 17
    • 8
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
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    Western Blotting (WB)
    交叉反应
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human MTH1
    亚型
    IgG
    Top Product
    Discover our top product NUDT1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NUDT1 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 1 (NUDT1))
    别名
    NUDT1 (NUDT1 产品)
    别名
    mutT antibody, nudT1 antibody, MTH1 antibody, Mth1 antibody, 7,8-dihydro-8-oxoguanine triphosphatase antibody, nudix hydrolase 1 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 1 antibody, mth1 antibody, Tsp_07498 antibody, nudt1 antibody, 8odp antibody, NUDT1 antibody, Nudt1 antibody
    背景
    Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008],MTH1,DNA Damage & Repair,Epigenetics & Nuclear Signaling,NUDT1
    分子量
    18 kDa
    基因ID
    4521
    UniProt
    P36639
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